重症监护病房患者复数菌感染的临床调查

目的探讨综合重症监护病房(ICU)复数菌感染病例的易感因素及感染病原菌。方法回顾性调查3年来综合ICU患者复数菌感染的诱发因素及相关病原菌。结果844例医院感染病例中，278例为复数菌感染(32．94％)；患者多为年龄偏大、住院时间较长，并伴有不同程度的基础疾病，加之抗生素、激素和免疫抑制剂的反复使用，侵袭性操作等因素均导致复数菌感染增多。结论复数菌感染病情危重难以控制，治愈率低，应积极治疗基础疾病；根据药物敏感试验结果针对性合理用药；严格消毒隔离制度，以降低复数菌的感染率。

Multi-bacterial Infection in Intensive Care Unit:A Clinical Investigation

QBJECTIVE To explore factors and agents of multi-bacterial infection in integration intensive careunit.METHODS Factors and agents of multi-bacterial infection in integration intensive care unit of our hospital during the last 3 years were retrospectively investigated. RESULTS Among 844 nosocomial infection cases,278 were caused by multi-bacterial infection (32.94%). Aging,long-period hospitalizing,accompanying with some underlying diseases,substantive using of antibiotics,hormone and immunity-depressive agents,and invasive treatment were all risk factors of multi-bacterial infection. CONCLUSIONS Positive treatment of underlying disease should be considered since multi-bacterial infections were hard to control. Rational using of drugs according to drug sensitivity test and strict sterilization and isolation measures should be taken to decline infection chances of multi-bacterial infection.