| 1－（2，6－二甲基苯氧基）－2－（3，4－二甲氧基苯乙氨基）丙烷盐酸盐对兔血小板胞浆游离钙浓度的影响 |
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| 引用本文： | 夏敬生,罗湘,曾繁典.1－（2，6－二甲基苯氧基）－2－（3，4－二甲氧基苯乙氨基）丙烷盐酸盐对兔血小板胞浆游离钙浓度的影响[J].药学学报,1996(11). |
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| 作者姓名： | 夏敬生 罗湘 曾繁典 |
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| 作者单位： | 同济医科大学临床药理研究室 |
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| 摘 要： | １－（２，６－二甲基苯氧基）－２－（３，４－二甲氧基苯乙氨基）丙烷盐酸盐对兔血小板胞浆游离钙浓度的影响夏敬生，罗湘，曾繁典（同济医科大学临床药理研究室，武汉４３００３０）１－（２，６－二甲基苯氧基）－２－（３，４－二甲氧基苯乙氨基）丙烷盐酸盐［１－（...
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| 关 键 词： | 1－（2，6－二甲基苯氧基）－2－（3，4－二甲氧基笨乙氨基）丙烷盐酸盐 血小板 钙离子 钙离子荧光指示剂（Fura－2） |
EFFECTS OF 1-(2,6-DIMETHYLPHENOXY)-2-(3,4-DIMETHOXY PHENYLETHYLAMINO)PROPANE HYDROCHLORIDE ON CYTOSOLIC FREE CALCIUM CONCENTRATION OF RABBIT PLATELETS |
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| JS Xia,X Luo and FD Zeng.EFFECTS OF 1-(2,6-DIMETHYLPHENOXY)-2-(3,4-DIMETHOXY PHENYLETHYLAMINO)PROPANE HYDROCHLORIDE ON CYTOSOLIC FREE CALCIUM CONCENTRATION OF RABBIT PLATELETS[J].Acta Pharmaceutica Sinica,1996(11). |
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| Authors: | JS Xia X Luo and FD Zeng |
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| Abstract: | The effects of 1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane hydrochloride(DDPH)and verapamil on cytosolic free calcium concentratiOn of rabbitplatelets were investigated.The results showed that the elevation of cytosolic free calciumconcentration(Ca2 ]i)of rabbit platelets following ionophore A23187 was significantly inhibited byDDPH and verapamil.The rates of inhibition with DDPH and verapamil were 58 % and 78 %,respectively,with no significant difference between the two groups(P>0.05). |
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| Keywords: | Dimethylphenoxy)-2-(3 4-dimethoxy phenylethylamino)propanehydrochloride Platelet Ca2 Fura-2 |
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