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乙酰水杨酸肠溶制剂的溶出度考察
引用本文:徐榕青,徐士尧,陈成辉. 乙酰水杨酸肠溶制剂的溶出度考察[J]. 中国医药工业杂志, 1996, 0(7)
作者姓名:徐榕青  徐士尧  陈成辉
作者单位:福建省医学科学研究所
摘    要:对国内7个生产厂家的乙酰水杨酸肠溶片及胶囊进行了体外耐酸性能及溶出度对比实验。结果表明各产品耐酸性能均符合规定,但溶出参数存在显著差异(p<0.01),T50最大相差6.1倍。空心肠溶胶囊质量对溶出度有极显著影响。

关 键 词:乙酰水杨酸,肠溶,溶出度

STUDY ON DISSOLUTION RATE OF ACETYLSALICYLIC ACID FROM ITS ENTERIC COATED TABLETS AND CAPSULES
XU Rong-Qing, XU Shi-Yao, CHEN Cheng-Hui. STUDY ON DISSOLUTION RATE OF ACETYLSALICYLIC ACID FROM ITS ENTERIC COATED TABLETS AND CAPSULES[J]. , 1996, 0(7)
Authors:XU Rong-Qing   XU Shi-Yao   CHEN Cheng-Hui
Abstract:The dissolution rates of acetylsalicylic acid (ASA) from its enteric coated tablets and capsules, produced by seven plants, were studied with rotating basket and the UV spectrophotometry. The results showed that the T50,Td and m of those samples had significant difference. The factors influencing the dissolution rates of ASA were discussed
Keywords:acetylsalicylic acid   enteric coated   tablet   capsule   dissolution  
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