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益气化痰通络方对股动脉粥样硬化和超敏C反应蛋白水平的影响
引用本文:陈敬贤,陈咸川. 益气化痰通络方对股动脉粥样硬化和超敏C反应蛋白水平的影响[J]. 上海中医药杂志, 2010, 0(2): 40-42
作者姓名:陈敬贤  陈咸川
作者单位:上海交通大学医学院附属瑞金医院中医科;上海中医药大学附属岳阳中西医结合医院老年科;
摘    要:目的观察益气化痰通络方对股动脉硬化患者股动脉内-中膜厚度(IMT)和超敏C反应蛋白(hs-CRP)的影响。方法将58例股动脉粥样硬化患者随机分为治疗组和对照组,对照组予降脂药辛伐他汀40mg/d,治疗组在对照组基础上加用益气化痰通络方(黄芪、当归、地龙、桑椹、丹参、茶树根、泽泻、石菖蒲等组成)。疗程均为12周。结果治疗组和对照组均可有效降低血清胆固醇、低密度脂蛋白浓度(P〈0.05,P〈0.01)。治疗组股动脉IMT均值较治疗前明显降低(P〈0.01),而对照组无明显改变,两组间差异有显著性(P〈0.01);治疗组和对照组血清hs-CRP均明显低于治疗前(P〈0.01,P〈0.05),且治疗组明显低于对照组(P〈0.05)。结论益气活血化痰通络方可消减股动脉粥样硬化,对IMT和hs-CRP有明显调节作用。

关 键 词:益气化痰通络方  股动脉粥样硬化  股动脉内-中膜厚度  超敏C反应蛋白

Effects of "Yiqi Huatan Tongluo Decoction" on femoral artery atherosclerosis and the level of hs-CRP
CHEN Jing-xian CHEN Xian-chuan. Effects of "Yiqi Huatan Tongluo Decoction" on femoral artery atherosclerosis and the level of hs-CRP[J]. Shanghai Journal of Traditional Chinese Medicine, 2010, 0(2): 40-42
Authors:CHEN Jing-xian CHEN Xian-chuan
Affiliation:CHEN Jing-xian1 CHEN Xian-chuan21.Ruijin Hospital,Shanghai Jiaotong University2.Yueyang Hospital of Integrated Chinese & Western Medicine Affiliated to Shanghai University of TCM
Abstract:Objective To observe the effect of "Yiqi Huatan Tongluo Decoction" on femoral artery's intima medial thickness(IMT) and the level of hs-CRP.Methods Fifty-eight patients with femoral artery atherosclerosis were randomized into two groups:control group was given Simvastatin(40 mg/d) and treatment group was given "Yiqi Huatan Tongluo Decoction",both with a course of 12 weeks.Results After treatment,serum total cholesterol,low density lipid was reduced in both treatment group and control group(P<0.05,P<0.01);th...
Keywords:"Yiqi Huatan Tongluo Decoction"  femoral artery atherosclerosis  femoral artery's intima medial thickness(IMT)  hs-CRP
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