| 砷对实验小白鼠某些生化指标的影响 |
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| 引用本文： | 潘秀琴 王连方. 砷对实验小白鼠某些生化指标的影响[J]. 地方病通报, 2000, 15(3): 10-12 |
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| 作者姓名： | 潘秀琴 王连方 |
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| 作者单位： | [1]新疆医科大学第一附属医院,新疆乌鲁木齐 [2]新疆地方病防治研究所,新疆乌鲁木齐 |
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| 基金项目： | 国家自然科学基金! (39660 0 71 ),卫生部科学研究基金!(96- 1 - 373) |
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| 摘 要： | 对砷暴露实验动物血清进行常用生化指标观察,结果显示２４项指标中除６项指标实验与对照组接近外,１８项指标有不同程度改变,其中ＢＵＮ、Ｎａ、ＡＬＢ、ＬＤＨ、ＡＬＰ、Ｃｒ、ＢＵＮ／Ｃｒ、ＢＧ等项两组有显差异,提示砷对动物生化指标有一定影响,为研究人类砷中毒生化指标变化提供线索。
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| 关 键 词： | 砷 生物化学 动物实验 白鼠 NIH |
Effects of Arsenic on Some Biochemical Indices in Experimental Mice |
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| PAN Xiu qin ,WANG Lian fang ,LIU Hui jun ,et al.. Effects of Arsenic on Some Biochemical Indices in Experimental Mice[J]. Endemic Diseases Bulletin, 2000, 15(3): 10-12 |
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| Authors: | PAN Xiu qin WANG Lian fang LIU Hui jun et al. |
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| Affiliation: | PAN Xiu qin 1,WANG Lian fang 2,LIU Hui jun 2,et al. |
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| Abstract: | Some common biochemical indices of mice serum from arsenic experiment were observed with an automatic biochemical analyzer. A total of 18 out of 24 indices observed had some changes between experimental group and control group. Compared with the control group, six indices (BUN, Na, ALB, LDH, ALP and BUN/Cr) increased obviously in the group of arsenic experiment. On the other hand, blood glucose and creatinine in experimental group were lower than that in control group. Some indices had better changes in the groups of protective cure with sulfydryl group preparation. The findings suggested that some biochemical indices could be interfered in arsenic intake, and rendered some clues of biochemistry change for human arsenic poisoning. |
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| Keywords: | Arsenic Biochemistry Animal experiment NIH mouse |
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