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Characterization of anaphylaxis reveals different metabolic changes depending on severity and triggers |
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| Authors: | Carolina Perales-Chorda David Obeso Laura Twomey Ayelén Rojas-Benedicto Leonor Puchades-Carrasco Marta Roca Antonio Pineda-Lucena José Julio Laguna Coral Barbas Vanesa Esteban Jaume Martí-Garrido Ethel Ibañez-Echevarria Ramón López-Salgueiro Domingo Barber Alma Villaseñor Dolores Hernández Fernández de Rojas |
| Affiliation: | 1. Allergy Department of Hospital, Universitari i Politècnic La Fe, Valencia, Spain These authors have equally contributed.;2. IMMA, Instituto de Medicina Molecular Aplicada, Departamento de Ciencias Médicas Básicas, Facultad de Medicina, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe| Boadilla del Monte, Madrid, 28660 Spain;3. IMMA, Instituto de Medicina Molecular Aplicada, Departamento de Ciencias Médicas Básicas, Facultad de Medicina, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe| Boadilla del Monte, Madrid, 28660 Spain CEMBIO, Centre for Metabolomics and Bioanalysis, Department of Chemistry and Biochemistry, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe| Boadilla del Monte, Madrid, 28660 Spain;4. Drug Discovery Unit, Health Research Institute La Fe, Valencia, Spain;5. Analytical Unit, Health Research Institute Hospital La Fe, Valencia, Spain;6. Drug Discovery Unit, Health Research Institute La Fe, Valencia, Spain Molecular Therapeutics Program, Center for Applied Medical Research, University of Navarra, Pamplona, Spain;7. Allergy Unit, Allergo-Anaesthesia Unit, Hospital Central de la Cruz Roja, Madrid, Spain;8. CEMBIO, Centre for Metabolomics and Bioanalysis, Department of Chemistry and Biochemistry, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe| Boadilla del Monte, Madrid, 28660 Spain;9. Faculty of Medicine and Biomedicine, Alfonso X El Sabio University, Madrid, Spain Department of Allergy and Immunology, IIS-Fundación Jiménez Díaz, UAM, Madrid, Spain;10. Allergy Department of Hospital, Universitari i Politècnic La Fe, Valencia, Spain |
| Abstract: | |
| Keywords: | 1H-NMR drug anaphylaxis food anaphylaxis grading anaphylaxis IgE-mediated anaphylaxis untargeted metabolomics UPLC-MS |