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髋关节置换术是否是妊娠的禁忌证
引用本文:蔡贵泉,陈晓东,朱俊峰.髋关节置换术是否是妊娠的禁忌证[J].解剖与临床,2012(5):430-432.
作者姓名:蔡贵泉  陈晓东  朱俊峰
作者单位:200092 上海市,上海交通大学医学院附属新华医院骨科
基金项目:国家自然科学基金面上项目(N0.81171705)和国家自然科学基金青年科学基金项目(No.81101381)
摘    要:目的:探讨髋关节置换术是否适用于育龄期妇女。方法:查阅近年来国外的相关文献,并做进一步综合分析。结果:从生物力学角度看,妊娠或分娩不会增加髋关节置换术后关节脱位、假体松动、假体周围骨折或翻修手术的风险,对临床、功能和放射学结果没有不良影响。金属关节假体可释放出金属离子钴和铬。金属离子有潜在的全身毒性反应,尤其是在金属对金属关节假体植入后几个月内。在分娩时,胎盘可减少钴和铬通过胎盘进入胎儿体内。结论:从生物力学角度看,髋关节置换术不应该认为是妊娠或分娩的禁忌证。对于接触钴铬颗粒和离子的长期生物学效应仍知之甚少。

关 键 词:全髋关节置换术  妊娠  分娩    

Is Hip Arthroplasty A Contraindication for Pregnancy
Institution:CAI Gui -quan, CHEN Xiao - dong, ZHU Jun -feng.( Department of Orthopaedics, Xinhua Hospital, Medical School of Shanghai Jiaotong University , Shanghai 200092, China)
Abstract:Objective:To investigate the application of hip arthroplasty in female patients of childbearing age. Methods:To look up the relevant foreign literatures in recent years, and make further comprehensive analysis. Results:From a biomechanical view, pregnancy or delivery does not improve the risk of dislocation, loosening, periprosthetic fracture, or revision surgery, there are no negative effects on clinical, functional and radiologea outcomes after hip arthroplasty. Metal implants release metal ions, cobalt and chromium, which, in turn, may cause potentially systemic toxicity, especially in the first few months from implantation of metal -on - metal prosthesis. At the time of delivery, the placenta reduces the passage of cobalt and chromium ions released from metal - on - metal prosthesis. Conclusions: From a biomechanical view, hip arthroplasty should not be considered a contraindication for pregnancy or spontaneous delivery. The long - term biological consequences of exposure to Co - Cr particles and ions remain little known.
Keywords:Total hip arthroplasty  Pregnancy  Delivery  Cobalt  Chromium
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