| 硝苯吡啶治疗高血压病疗效分析 |
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| 引用本文： | 周宏研,胡凯,孙明,王智纯,郭远能,王振华. 硝苯吡啶治疗高血压病疗效分析[J]. 中南大学学报(医学版), 1987, 0(2) |
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| 作者姓名： | 周宏研 胡凯 孙明 王智纯 郭远能 王振华 |
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| 作者单位： | 湖南医学院第一附属医院内科(周宏研，胡凯，孙明，王智纯)，湖南省商业厅职工医院(郭远能)，湖南医学院第一附属医院内科(王振华) |
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| 摘 要： | 用国产硝苯吡啶(心痛定)口服治疗高血压病患者36例,症状及降压疗效分别达94.4%及83.3%,效果满意,心功能有明显改善,在降低血压的同时,有改善心脏功能作用,因而可做为一种有前途的降血压药物。
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| 关 键 词： | 高血压 硝苯吡啶 药效学 药物疗法 心脏功能试验 |
ANALYSIS OF ANTI-HYPERTENSIVE EFFECT OF NIFEDIPINE |
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| Zhou Hongyan,Hu Kai,Sun Ming,Wang Zhichun,Guo Yuanneng,Wang Zhenhua. ANALYSIS OF ANTI-HYPERTENSIVE EFFECT OF NIFEDIPINE[J]. Journal of Central South University. Medical sciences, 1987, 0(2) |
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| Authors: | Zhou Hongyan Hu Kai Sun Ming Wang Zhichun Guo Yuanneng Wang Zhenhua |
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| Affiliation: | Zhou Hongyan,Hu Kai,Sun Ming,Wang Zhichun,Guo Yuanneng,Wang Zhenhua Department of Internal Medicine,The First Affiliated Hospital,Hunan Medical College |
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| Abstract: | Thirty-six patients with mild or moderate hypertension were treated withnifcdipine for two to three months.The drug relieved symptoms,especiallyhee.daches,in 94.4% of the patients.Nifedipine lowered blood pressure in 83.3%of the patients with 70% reaching normaldiastolic levels.These levels were achieved within a week and remained steady throughout the observation period.When diastolic heart function was checked at the end of the study period,theA/H and A/D ratios were shown to be decreased as compared to levels beforetreatment,the A_2OI and DATI were prolonged all to a statistically significantdegree.Above changes reflect the improvement of diastolic heart function.It isconsidered that nifedipine could be a valuable anti-hypertensive agent. |
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| Keywords: | Hypertension Nifedipine Pharmacodynamics Drug therapy Heart function test |
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