| 2型糖尿病患者踝肱指数与胰岛素抵抗的相关性 |
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| 引用本文： | 潘颖,胡仁明,朱文华,沈鲜安,钟绍.2型糖尿病患者踝肱指数与胰岛素抵抗的相关性[J].中国医疗前沿,2009(5):13-13,2. |
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| 作者姓名： | 潘颖 胡仁明 朱文华 沈鲜安 钟绍 |
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| 作者单位： | [1]复旦大学附属华山医院内分泌科,上海200040 [2]江苏大学附属昆山市第一人民医院内分泌科,江苏昆山215300 |
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| 摘 要： | 目的探讨2型糖尿病患者踝肱指数（ABI）与胰岛素抵抗之间的关系。方法根据糖化血红蛋白的水平把72例糖尿病患者分成DM1组和DM2组,与35例对照组ABI、空腹血糖（FBG）、糖化血红蛋白（HbA1C）、空腹血清胰岛素、胰岛素抵抗指数（HOMA-IR）进行对照,并对ABI和HOMA-IR进行相关性分析。结果2型糖尿病患者的ABI值与FBG（r=-0.43,P〈0.05）、HbA1C（r=-0.52,P〈0.01）和HOMA-IR（r=-0.48,P〈0.05）呈显著负相关。结论2型糖尿病患者的ABI值与血糖控制程度和胰岛素抵抗密切相关。
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| 关 键 词： | 糖尿病 2型 胰岛素抵抗 踝肱指数 |
Relationship between ankle-brachial index and insulin resistance in patients with type 2 diabetes mellitus |
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| Institution: | PAN Ying, HU Ren-ming, ZHU Wen-hua (1.Department of Endocrinology, Huashan Hospital of Fudan University, Shanghai 200040, China, 2 .Department of Endocrinology, The first Kunshan Hospital of Jiangsu University, Kunshan Jiangsu 215300, China) |
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| Abstract: | Objective To study the relationship between lower extremity arterial disease and insulin resistance in patients with type 2 diabetes mellitus. Methods 72 diabetic patients were divided into DM1 group and DM2 group according to HbA1C. ABI,FBG,HbA1C,F-INS and HOMA-IR were measured on 72 subjects with type 2 diabetes and 35 control subjects. Correlation analysis was conducted between ABI and HOMA-IR. Results ABI had negative relation with FBG （r =-0.43, P〈0.05 ） ,HbA1C （r =-0.52, P〈0.01 ） ,HOMA-IR （ r = -0.48, P〈0.05 ）. Conclusion The changes of ABI in type 2 diabetes mellitus were in close relationship with the level of blood sugar and insulin resistance. |
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| Keywords: | Diabetes mellitus type 2 Peripheral arterial disease Insulin resistance |
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