药品集中招标采购对安徽省5家县级公立医院抗菌药物使用的影响

目的:分析安徽省县级公立医院药品集中招标采购对医院抗菌药物使用的影响。方法:选取安徽省5家县级公立医院,对药品集中招标采购前后抗菌药物的采购品种、配送金额、用药频度(DDDs)和日均治疗费用(DDC)等进行统计分析。结果:招标后抗菌药物的品种数、配送金额和DDDs,除单环类药物的配送金额大幅下降外,均呈增长趋势且排名前三位的药品类别与招标前相同,分别为头孢菌素类、复方制剂和喹诺酮类。注射用阿莫西林克拉维酸钾的DDDs排序在招标前后始终位居第一位。DDDs排序前十位抗菌药物中有8种药物招标后DDC呈下降趋势。结论:药品集中招标降低了医院多数抗菌药物的DDC,使合理用药趋势较招标前有所提高,但仍然需要进一步完善,使药品集中招标采购真正做到为促进医疗机构合理用药发挥积极作用。

Effect of the centerized bidding system of drug on the use of antibacterials in five country public hospitals in Anhui Province

Objective:To analyze the effects of the centerized bidding system of drug on the use of antibacterials in five county public hospitals in Anhui province. Methods:The purchasing varieties,distribution amount,defined daily dose system( DDDs) and DDC of antibacterials in five county public hospitals before and after the bidding were analyzed. Results:After bidding,except for monocyclic drug,the varieties,shipping amount and DDDs of antibacterials increased obviously. The categories of the top three drugs after bidding were cephalosporins, compound preparation and quinolones, respectively, which was the same as before bidding. The DDDs of clavulanate potassium injection ranked was the first before and after bidding. Among the top 10 ranking antibacterials in DDDs,the DDC in 8 kinds of drugs decreased after bidding. Conclusions:The centerized bidding system of drug reduces the DDC of many antibacterials,and improves the rational use of drugs. Improving the centerized bidding system can play a positive role in promoting the rational use of drugs in medical institutions.