| 葡多酚与辐照对小鼠S180肉瘤的协同抑制作用研究 |
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| 引用本文： | 钟进义,粟世如.葡多酚与辐照对小鼠S180肉瘤的协同抑制作用研究[J].癌变．畸变．突变,1999,11(5):264-266. |
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| 作者姓名： | 钟进义 粟世如 |
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| 作者单位： | 青岛大学医学院!青岛266021 |
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| 摘 要： | 为了探讨葡多酚对肿瘤放射的协同作用，将荷Ｓ１８０肉瘤小鼠分别给予＾６０Ｃｏγ射线局部照射，口服ＧＰＣ和局部照射加口服ＧＰＣ等不同方法处理，接种瘤细胞后第１２天，检测动物的瘤重，血白细胞计数，脾淋巴细胞转化率指标。
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| 关 键 词： | 葡多酚 放射治疗 抑瘤作用 |
THE COOPERATIVE INHIBITION EFFECT OF GRAPE PROCYANIDIN AND RIDIOTHERAPY ON SARCOCARCINOMA S180 OF MICE |
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| Abstract: | To study the role of grape procyanidin(GPC) in radiotherapy treatment for tumor, The mice inoculated sarcocarcinoma S\-\{180\} was treated by local irradiation, GPC feeding and irradiation+GPC respectivly. The tumor weight and other indexs were examined at 12th day after tumor inoculation. The resluts showed the average weight of tumor of mice in control group was higher than that of in other groups, the inhibitory rate of tumor in the group of irradiation+high dose of GPC was higher than both group irradiation or GPC, and the WBC count of mice in irradiation group was lower than other groups. All differenees above are significant in statistics. It suggests GPC has a improve effect to the radiotherapy of tumor. |
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| Keywords: | grape procyanidin radiotherapy tumor inhibitory effect |
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