长托宁治疗急性有机磷农药中毒的疗效观察

目的 观察长托宁治疗急性有机磷农药中毒的临床疗效.方法 将急性有机磷农药中毒的48例患者随机分为2组,比较长托宁和阿托品治疗急性有机磷农药中毒的临床疗效.结果 两组患者的用药次数,症状消失时间,CHE恢复时间及治愈时间经统计学分析,P<0.01,有显著性差异.长托宁组痊愈率为91.67%,死亡率为8.33%:阿托品组痊愈率为70.83%,死亡率为29.17%,两组患者的痊愈和死亡情况经统计学分析,P<0.05,有差异性.结论 长托宁治疗急性有机磷农药中毒的临床疗效优于阿托品.治愈率高,死亡率低,值得临床推广使用.

The Clinical Observation of Penehyclidine Hydrouhloride Injection on Treating Acute Organophosphorus Pesticide Poisoning

Objective To observe the clinical efficacy of Penehyclidine Hydrochloride Injection on treating acute onganophosphorus pesticide poisoning, Methoda The acute organophosphorus pesticide poisoning 48 patiants were randomly divided into 2 groups to compare the clinical efficacy of Penehyclidine Hydrochloride Injection and Atropine on treating acute organophosphorus pesticide poisoning. Resu Its By the statistical analysis(the two groups of patients' drug use frequency, symptoms disappeared time, CHE recovery time and healing time), there is significant difference for P< 0.01.For Penehyclidine Hydrochloride Injection set, the cure rate is 91.67 percent, mortality rate is 8.33 percent.For Atropine set, the cure rate is 70.83 percent, mortality rate is 29.17 percent. For the two groups of patients with healed and death by the statistical analysis, P<0.05, there is difference. Conclusion The clinical efficacy of Penehyclidine Hydrochloride Injection on treating acute organophosphorus pesticide poisoning is better than that of Atropine. Penehyclidine Hydrochloride Injection has a high cure rate, low mortality, so it is worth for clinical use.