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葡萄球菌感染的耐药性监测和治疗对策
引用本文:邓健康,霍亚平,郭晓兰.葡萄球菌感染的耐药性监测和治疗对策[J].中国误诊学杂志,2005,5(14):2615-2616.
作者姓名:邓健康  霍亚平  郭晓兰
作者单位:川北医学院附属医院检验科,四川,南充,637000
摘    要:目的:了解葡萄球菌的耐药情况,指导临床合理使用抗生索。方法:用VITEK-32、GPI、GPS-107进行菌种鉴定、耐甲氧西林葡萄球菌(MRS)检测和药敏实验。结果:188株葡萄球菌中凝固酶阴性葡萄球菌(CNS)136株,其中耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)120株,检出率为88.2%。MRS对万古霉索、呋喃妥因100%敏感,对利福平敏感性高。结论:我院MRS检出率较高,应重视对MRS耐药性的监测,治疗由MRS菌株引起的严重感染应首选万古霉素。

关 键 词:葡萄球菌属/药物作用  抗药性  细菌  菌药/治疗应用  葡萄球菌感染/药物疗法
文章编号:1009-6647(2005)14-2615-02
收稿时间:08 29 2005 12:00AM
修稿时间:09 2 2005 12:00AM

Study on Antimicrobial Resistance and Therapeutic Strategy on Staphylococcus Infections
DENG Jian-kang,HUO Ya-ping,GUO Xiao-lan.Study on Antimicrobial Resistance and Therapeutic Strategy on Staphylococcus Infections[J].Chinese Journal of Misdiagnostics,2005,5(14):2615-2616.
Authors:DENG Jian-kang  HUO Ya-ping  GUO Xiao-lan
Institution:Department of Clinical Laboratory ,Affiliated Hospital of North Sichuan Medical College, Nanchong,Sichuan, 637000
Abstract:Objective:To survey the resistance of Staphylococcus,and to provide the reference for the clinical antimicrobial agents usage.Methods:The identification and drug susceptibility tests were carried out with Vitek-32,GPI and GPS-107 for Staphylococcus.Results:Among 188 strains of staphylococcus,136 trains wereresistant coagulase negative staphylococcus (CNS),of which 120 were methicillin coagulase negative staphylococcus(MRS)with thedetectiong rate of 88.2%.MRS was susceptible to vancomycin, nitrofurantoin and rifampin.Conclusions:We should pay much attention to detecting MRS, the resistance of MRS to antibiotics should be further monitored. Vancomycin may be used for the treatment of MRS infection first.
Keywords:Staphylococcus/drug effects Drug resistance  bacterical Anti-bacterial agents/therapeutic use Staphylococcal infections/drug therapy
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