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Silent mixed growth hormone cell-prolactin cell pituitary adenoma
Authors:Shigeru Furuhata  Toru Kameya  Mitsuhiro Otani  Yoshinori Shimamoto  Hideo Asada  Shigeo Toya
Institution:1. Department of Neurosurgery, Keio University School of Medicine, Tokyo
3. Department of Pathology, Kitasato University School of Medicine, Kanagawa, Japan
Abstract:The case of a 51 -year-old man with recurrent nonfunctioning pituitary adenoma is presented. Despite clinically and endocrinologically normal pituitary function in regard to growth hormone and prolactin, many growth hormone- and prolactin-positive cells were immunohis-tochemically detected in adenoma tissue. Furthermore, a quite rare tumor of silent mixed growth hormone cell-prolactin cell pituitary adenoma was confirmed by the double-labeling immunoelectron-microscopical study.
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