蒙特利尔认知评估量表与简易精神状态检查用于评定阿尔茨海默病患者认知功能的比较

目的:比较蒙特利尔认知评估量表(MoCA)中文版与简易精神状态检查(MMSE)评定阿尔茨海默病(AD)患者及正常人的结果,并分析MoCA中文版的特征。方法:以王炜等的中文版为蓝本,对2组对象进行测试。病例组(56例):男30例,女26例,年龄(56.3±12.2)岁。对照组(78例):男36例,女42例,年龄(46.8±14.5)岁。分别用MoCA和MMSE评定2组对象。将MoCA结果与MMSE结果作相关性检验及项目内容比较。结果:MoCA和MMSE评定结果总分高度相关(r=0.898,P0.001)。两者所需时间大致相当。结论:MoCA中文版可以用于AD患者的认知评定。

Comparison of cognitive assessment in subjects with Alzheimer's disease between Montreal cognitive assessment Chinese version and mini-mental state examination

Objective:To assess the cognitive function of subjects with or without Alzheimer's disease (AD) with Chinese version of Montreal cognitive assessment (MoCA) and mini-mental state examination (MMSE) and to analyze the characteristic of Chinese version of MoCA. Method: Chinese version of MoCA was translated by Wang Wei. Fifty-six patients with AD were selected as patient group, and seventy -eight subjects without neurological disorders participated as control group. All the subjects were assessed with MoCA and MMSE and the results were analyzed. Result: There was high correlation between the scores of MoCA and MMSE (r=0.898,P<0.001). To perform the assessment of Chinese version of MoCA needed to take the same time as that of MMSE. Conclusion: Chinese version of MoCA could be used as a tool in clinical study of cognitive function for AD.