| 肺癌患者血清CEA、NSE、CA19-9和VEGF检测的临床意义 |
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| 引用本文： | 辜彦,王裕圯.肺癌患者血清CEA、NSE、CA19-9和VEGF检测的临床意义[J].放射免疫学杂志,2009,22(4):332-334. |
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| 作者姓名： | 辜彦 王裕圯 |
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| 作者单位： | 江苏省灌南县人民医院检验科,222500 |
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| 摘 要： | 目的：探讨了血清CEA、NSE、CA19-9和VEGF水平在肺癌患者中的变化。方法：分别应用放射免疫分析和ELISA对31例肺癌患者进行了血清CEA、NSE、CA19-9和VEGF测定,并与35名正常健康人作比较。结果：肺癌患者血清CEA、NSE、CA19-9和VEGF水平均非常显著地高于正常人组（P〈0.01）,且CEA、NSE、CA19-9和VEGF呈明显正相关（r=0.6218、0.6101、0.6317,P〈0.01）。结论：检测肺癌患者血清CEA、NSE、CA19-9和VEGF水平的变化对了解病情、指导临床实践均具有重要的临床价值。
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| 关 键 词： | 肺癌 癌胚抗原 神经元特异性烯醇化酶 糖类抗原-19-9 血管内皮生长因子 |
Clinical Significance of Determination of Changes of Serum CEA,NSE,CA19-9 and VEGF Levels in Patients with Lung Cancer |
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| Gu Yan,Wang Yuyi.Clinical Significance of Determination of Changes of Serum CEA,NSE,CA19-9 and VEGF Levels in Patients with Lung Cancer[J].Journal of Radioimmanology,2009,22(4):332-334. |
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| Authors: | Gu Yan Wang Yuyi |
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| Institution: | Gu Yan,Wang Yuyi Department of Clinical Laboratory Medicine,Guannan county people's Hospital,Guannan(222500),China |
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| Abstract: | Objective To explore the clinical significance of changes of serum CEA,NSE,CA19-9 and VEGF levels in patients with lung cancer.Methods Serum CEA,NES,CA19-9(with RIA)and VEGF(with ELISA) levels were detected in 31 patients with lung cancer and 35 controls.Results The levels of serum CEA,NSE,CA19-9 and VEGF were significantly higher in the patients than those in controls(P<0.01).Serum CEA,NSE,CA19-9 levels were positively correlated with the VEGF levels(r=0.6218,0.6101,0.6317,P<0.01).Conclusion Serum CEA,NSE,... |
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| Keywords: | lung cancer carcinoembryonic antigen(CEA) neuron-specific enolase(NSE) carbohydrate antigen 19-9(CA19-9) vascular endothelial growth factor(VEGF) |
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