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膀胱尿路上皮癌伴腺性分化临床病理观察
引用本文:冷冬妮,刘志,刘英娜,闵慧,王珺. 膀胱尿路上皮癌伴腺性分化临床病理观察[J]. 东南国防医药, 2011, 13(6): 512-514
作者姓名:冷冬妮  刘志  刘英娜  闵慧  王珺
作者单位:1. 解放军454医院病理科,江苏南京,210002
2. 马鞍山市人民医院病理科,安徽马鞍山,243000
摘    要:目的探讨膀胱尿路上皮癌伴腺性分化的病理诊断与鉴别。方法采用HE和免疫组化(EnVision法)观察10例膀胱尿路上皮癌伴腺性分化的形态学及免疫组化特征。结果 10例肿瘤平均直径为2.5 cm,呈菜花状、息肉状、蕈伞状或溃疡状。组织学以尿路上皮癌与腺性成分混合为特征。免疫组化CKpan阳性(10/10)、p63阳性(10/10),Ki-67阳性(10/10,20%~60%),p53阳性(10/10,10%~20%),PSA、P504S、CgA、Syn及SMA均阴性。结论该肿瘤是一种少见的膀胱肿瘤,需与膀胱其他多种疾病鉴别。

关 键 词:膀胱肿瘤  尿路上皮癌  病理学

Clinicopathological observation of urothelial carcinoma of the bladder with glandular differentiation
LENG Dong-ni,LIU Zhi,LIU Ying-na,MIN Hui,WANG Jun. Clinicopathological observation of urothelial carcinoma of the bladder with glandular differentiation[J]. Journal of Southeast China National Defence Medical Science, 2011, 13(6): 512-514
Authors:LENG Dong-ni  LIU Zhi  LIU Ying-na  MIN Hui  WANG Jun
Affiliation:LENG Dong-ni1,LIU Zhi2,LIU Ying-na1,MIN Hui1,WANG Jun1.1.Department of Pathology,454 Hospital of PLA,Nanjing,Jiangsu 210002,China,2.Department of Pathology,the People's Hospital of Maanshan,Maanshan,Anhui 243000
Abstract:Objective To study the pathological diagnosis and differential diagnosis of urothelial carcinoma of the bladder with glandular differentiation.Methods The morphological and immunohistological features of ten cases of urothelial carcinoma of the bladder with glandular differentiation were investigated with H&E staining and EnVision immunostaining.Results The tumors were mean diameter 2.5 cm in size,cauliflower-like,polypoid,mushroom-like and ulcer-like in naked eye.Histologically,all cases showed presence of...
Keywords:tumor of the bladder  urothelial carcinoma  pathology  
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