| 经络舒胶囊对糖尿病大鼠血糖及糖化血红蛋白含量水平的影响 |
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| 引用本文： | 张永萍,孔德明,徐剑,徐莛婷.经络舒胶囊对糖尿病大鼠血糖及糖化血红蛋白含量水平的影响[J].中华中医药杂志,2011(12):2870-2871. |
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| 作者姓名： | 张永萍 孔德明 徐剑 徐莛婷 |
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| 作者单位： | 贵阳中医学院药学系;贵阳中医学院第一附属医院; |
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| 基金项目： | 贵州省中药现代化科技产业研究开发专项项目(No.黔科合农字[2005]5001号)~~ |
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| 摘 要： | 目的:观察经络舒胶囊对糖尿病大鼠血糖、糖化血红蛋白含量水平的影响。方法:Wistar大鼠腹腔注射链脲佐菌素(STZ)制成糖尿病大鼠模型。将动物随机分为正常对照组、模型对照组、西药阳性对照组(胰岛素)、中药阳性对照组(糖脉康)、经络舒胶囊高、中、低剂量组。给药60d以后测定大鼠空腹血糖浓度及糖化血红蛋白含量。结果:与模型对照组比较,胰岛素对照组能明显降低糖尿病大鼠空腹血糖水平(P<0.01)。与模型对照组比较,胰岛素对照组和高剂量组能明显降低糖尿病大鼠糖化血红蛋白水平(P<0.05)。结论:高剂量组的经络舒胶囊能明显降低糖尿病大鼠糖化血红蛋白水平,为该制剂临床上用于糖尿病神经病变包括外周神经炎和糖尿病植物神经功能紊乱提供了实验理论依据。
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| 关 键 词： | 经络舒胶囊 糖尿病大鼠 血糖 糖化血红蛋白 |
Effect of Jingluoshu Capsule on blood glucose and GHb levels in diabetic rats |
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| ZHANG Yong-ping,KONG De-ming,XU Jian,XU Ting-ting.Effect of Jingluoshu Capsule on blood glucose and GHb levels in diabetic rats[J].China Journal of Traditional Chinese Medicine and Pharmacy,2011(12):2870-2871. |
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| Authors: | ZHANG Yong-ping KONG De-ming XU Jian XU Ting-ting |
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| Institution: | ZHANG Yong-ping1,KONG De-ming2,XU Jian1,XU Ting-ting1(1Department of Pharmacy,Guiyang College of TCM,Guiyang 520002,China,2The First Affiliated Hospital of Guiyang College of TCM,Guiyang 520001,China) |
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| Abstract: | Objective: To observe the influence of Jingluoshu Capsule on blood glucose and GHb levels in diabetic rats.Methods: Wistar rats were injectd with intraperitoneal STZ to establish their diabetic model.Animals were randomLy divided into four groups: normal group,model group,insulin group,Tangmaikang group and Jingluoshu capsu high/middle/low dose group.The fasting blood glucose concentration and glycated hemoglobin levels of rats were determined in 60 days later op.Results: Compared with the model group,insul... |
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| Keywords: | Jingluoshu Capsule Diabetic rats Blood glucose Glycated hemoglobin |
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