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腺苷蛋氨酸治疗慢性乙型肝炎疗效观察
引用本文:陈明胜,刘宁,林建辉,江晓燕.腺苷蛋氨酸治疗慢性乙型肝炎疗效观察[J].福建医药杂志,2011,33(5):98-100.
作者姓名:陈明胜  刘宁  林建辉  江晓燕
作者单位:福建医科大学附属传染病医院福州市传染病医院,福州,350001
摘    要:目的 观察腺苷蛋氨酸治疗胆红素升高的慢性乙型肝炎的疗效.方法 对120例胆红素升高的慢性乙型肝炎患者资料进行回顾性分析.观察组60例在甘草酸类保肝药物治疗基础上加用腺苷蛋氨酸治疗,对照组60例仅接受甘草酸类药物治疗,疗程2周,分别观察治疗前后血清TBiL、DBiL、ALT、AST、γ-GT、ALP的变化.结果 两组经治...

关 键 词:腺苷蛋氨酸  慢性乙型肝炎

Clinical curative effect of S-Adenosylmethionine in treating chronic hepatitis B with hyperbilirubinemia
CHEN Ming-sheng,LIU Ning,LIN Jian-hui,JIANG Xiao-yan.Clinical curative effect of S-Adenosylmethionine in treating chronic hepatitis B with hyperbilirubinemia[J].Fujian Medical Journal,2011,33(5):98-100.
Authors:CHEN Ming-sheng  LIU Ning  LIN Jian-hui  JIANG Xiao-yan
Institution:CHEN Ming-sheng,LIU Ning,LIN Jian-hui,JIANG Xiao-yan.Affiliated Hospital for Infectious Diseases of Fujian Medical University,Fuzhou Hospital for Infectious Diseases,Fuzhou 350001,China
Abstract:Objective To observe the clinical curative effect of S-Adenosylmethionine(SAMe) in treating chronic hepatitis B with hyperbilirubinemia.Methods To retrospectively analyse 120 cases of chronic hepatitis B patients with hyperbilirubinemia.Sixty cases treated with both glycyrrhizin therapy and SAMe were considered as the treatment group while the other 60 cases treated with only glycyrrhizin therapy as the control group.Serum TBiL,DBiL,ALT,AST,γ-GT and ALP were observed and compared before and two weeks after the treatments.Results After treatments,significant declines in the levels of serum TBiL DBiL ALT and AST were observed in both groups,and also in γ-GT and ALP in the treatment group.The levels of TBiL DBiL ALT AST γ-GT and ALP dropped more in the treatment group than control group.Conclusion SAMe can improve liver function and is a good treatment for chronic hepatitis B with hyperbilirubinemia.
Keywords:S-Adenosylmethionine  chronic hepatitis B  
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