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论“四时之肝”对季节性情感障碍发病的“生物钟”作用机制
引用本文:杨阳,马淑然,王庆国,蒲晓田,陈玉萍,支政,杜媛鲲,张灵敏,刘艳.论“四时之肝”对季节性情感障碍发病的“生物钟”作用机制[J].中华中医药杂志,2011(11):2529-2532.
作者姓名:杨阳  马淑然  王庆国  蒲晓田  陈玉萍  支政  杜媛鲲  张灵敏  刘艳
作者单位:北京中医药大学;河北医科大学;
基金项目:国家重点基础研究发展计划(973计划)(No.2001CB505101); 河北省中医药管理局中医药类科研计划课题(No.2011074)~~
摘    要:文章就季节性情感障碍(SAD)的中医发病机制进行了理论探讨。认为"四时之肝"对SAD的发病具有"生物钟"作用。在SAD的季节性发病和缓解的四时,"四时之肝"的作用如同一个循环无端的"生物钟",遵循着生、长、收、藏的"S曲线"变化规律。SAD的发病是"四时之肝"的"生物钟"调节紊乱的结果。根据四时阴阳消长规律,校正肝脏"生物钟"的四时节律曲线,对于临床防治SAD将提供新的启迪。

关 键 词:五脏应时    季节性情感障碍  生物钟

The 'Biological Clock' mechanism of 'Seasonal Liver' to the attack of seasonal affective disorder
YANG Yang,MA Shu-ran,WANG Qing-guo,PU Xiao-tian,CHEN Yu-ping,ZHI Zheng,DU Yuan-kun,ZHANG Ling-min,LIU Yan.The 'Biological Clock' mechanism of 'Seasonal Liver' to the attack of seasonal affective disorder[J].China Journal of Traditional Chinese Medicine and Pharmacy,2011(11):2529-2532.
Authors:YANG Yang    MA Shu-ran  WANG Qing-guo  PU Xiao-tian  CHEN Yu-ping  ZHI Zheng  DU Yuan-kun  ZHANG Ling-min  LIU Yan
Institution:YANG Yang1,2,MA Shu-ran1,WANG Qing-guo1,PU Xiao-tian1,CHEN Yu-ping1,ZHI Zheng2,DU Yuan-kun2,ZHANG Ling-min2,LIU Yan2 (1Beijing University of Chinese Medicine,Beijing 100029,China,2Hebei Medical University,Shijiazhuang 050017,China)
Abstract:The article discusses the TCM pathogenesis of Seasonal Affective Disorder(SAD) from theoretical aspects.The authors consider that 'Seasonal Liver' shows the 'Biological Clock' role to SAD.During the four seasons,SAD appears or be relieved with seasons' changing.'Seasonal Liver' shows the role just like a circulatory and unprovoked 'Biological Clock'.It changes according to the S curve of spring's germinal,summer's growing,autumn's convergence.The attack of SAD is the result of 'Biological Clock' adjustment ...
Keywords:Correspondence between five visceras and seasons  Liver  Seasonal affective disorder  Biological clock  
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