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Minocycline: old and new therapeutic uses |
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| Authors: | Freeman C D Nightingale C H Quintiliani R |
| Affiliation: | a Department of Pharmacy Practice, College of Pharmacy, Butler University, Indianapolis, IN 46208, USA b Department of Pharmacy, Community Hospital East, Indianapolis, IN, USA c Hartford Hospital, Hartford, CT, USA d School of Pharmacy, University of Connecticut, Storrs, CT, USA e Division of Infectious Diseases and Immunology/Allergy, Department of Medicine, Hartford Hospital, Hartford, CT, USA f School of Medicine, University of Connecticut Medical Center, Farmington, CT, USA |
| Abstract: | Since the introduction of minocycline HCl in the late 1960's, it has been used for disease states that have ranged from typical community-acquired infectious diseases to others that are non-infectious, such as resistant rheumatoid arthritis. Owing to its high penetration characteristics throughout the body, minocycline can be used in the treatment of a wide variety of extracellular and intracellular pathogens. This review examines the known and potential therapeutic uses of minocycline in a clinical setting. |
| Keywords: | Minocycline, pharmacokinetics, therapeutic uses Prostatitis/Urethritis Neisseria meningtidis Cystic fibrosis Staphylococcus aureus Mycobacteria Nocardia Toxoplasma gondii Periodonitis Rheumatoid arthritis Infertility |
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