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| 纳米银温敏喷雾凝胶与环丙沙星联合应用体外抑菌作用 | |
| 引用本文： | 陈美婉,刘长秀,余思琴,杨志文,吴传斌. 纳米银温敏喷雾凝胶与环丙沙星联合应用体外抑菌作用[J]. 中国消毒学杂志, 2012, 29(1): 18-19,22 |
| 作者姓名： | 陈美婉 刘长秀 余思琴 杨志文 吴传斌 |
| 作者单位： | 1. 中山大学药学院,广州510006;广东省创新药物制剂工程技术研究开发中心;;澳门大学中华医药研究院; 2. 中山大学基础医学实验教学中心 3. 中山大学药学院,广州510006;广东省创新药物制剂工程技术研究开发中心 |
| 摘 要： | 目的观察纳米银温敏喷雾凝胶与环丙沙星联合应用的体外抑菌作用,探讨其抗菌应用价值。方法用K-B纸片扩散法,对上述两种制剂联合应用抑菌效果进行了测定。结果纳米银温敏喷雾凝胶抗菌效果良好,可以增强环丙沙星对金黄色葡萄球菌,大肠埃希菌和铜绿假单胞菌的抑制作用。结论纳米银温敏喷雾凝胶联用环丙沙星体外的联合应用具有良好的可行性。 |
| 关 键 词： | 纳米银 喷雾凝胶 环丙沙星 联合应用 抑菌作用 |
THE ANTIBACTERIAL EFFECT OF TEMPERATURE -SENSITIVE GEL CONTAINING SILVER NANOPARTICLES COMBINED WITH CIPROFLOXACIN in vitro |
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| CHEN Mei-wan , LIU Chang-xiu , YU Si-qin , YANG Zhi-wen , WU Chuan-bin. THE ANTIBACTERIAL EFFECT OF TEMPERATURE -SENSITIVE GEL CONTAINING SILVER NANOPARTICLES COMBINED WITH CIPROFLOXACIN in vitro[J]. Chinese Journal of Disinfection, 2012, 29(1): 18-19,22 | |
| Authors: | CHEN Mei-wan LIU Chang-xiu YU Si-qin YANG Zhi-wen WU Chuan-bin |
| Affiliation: | 1,2(1 College of Pharmaceutical Science,Sun Yat-sen University,Guangzhou 510006;2 Research & Development Center of Pharmaceutical Engineering,Sun Yat-sen University,Guangzhou;3 Institute of Chinese Medical Sciences,University of Macau;4 Experimental Teaching Center of Basic Medicine,Sun Yat-sen University,Sun Yat-sen University,Guangzhou,China) |
| Abstract: | Objective To study the antibacterial effect of temperature-sensitive gel containing silver nanoparticles combined with ciprofloxacin in vitro and to investigate its potential value.Methods The K-B test was used to observe the antibacterial effect of temperature-sensitive gel containing silver nanoparticles combined with ciprofloxacin.Results The temperature-sensitive gel containing silver nanoparticles could strengthen the antibacterial activity of ciprofloxacin against Staphylococcus auresus,Escherichia coli,and Pseudomonas aeruginosa.Conclusion The application of temperature-sensitive gel containing silver nanoparticles combined with ciprofloxacin in vitro is feasible. |
| Keywords: | silver nanoparticles atomization gelatin ciprofloxacin combined application bacteriostatic effect |
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