| 呼吸病区抗菌药物使用量与铜绿假单孢菌耐药的相关性分析 |
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| 引用本文： | 杨新云,肖翔林,陈文瑛,袁锦屏,杨灵.呼吸病区抗菌药物使用量与铜绿假单孢菌耐药的相关性分析[J].海峡药学,2007,19(6):108-110. |
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| 作者姓名： | 杨新云 肖翔林 陈文瑛 袁锦屏 杨灵 |
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| 作者单位： | 广州医学院第一附属医院,广州,510120;广州呼吸疾病研究所,广州,510120 |
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| 基金项目： | 广东省广州市卫生局科研项目 |
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| 摘 要： | 目的 探讨2004～2006年呼吸病区抗菌药物使用与铜绿假单孢菌(PA)耐药水平变化之间的关系.方法 计算12种抗菌药物平均每日每百张床位所消耗的DDDs及同期PA的耐药率,并对抗菌药物用量与耐药率进行相关性分析.结果 FEP、CFS、MEM的使用量分别与PV对CIP、LEV、CTX的耐药率呈显著相关性;而LEV的使用量又分别与PV对CFS和IPM的耐药率呈显著相关性.结论 呼吸病区FEP、CFS、MEM、LEV的使用量与PA耐药率呈显著相关性.
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| 关 键 词： | 铜绿假单孢菌 耐药性 抗菌药物用量 |
| 文章编号： | 1006-3765（2007）06-0108-03 |
Analysis of the correlation between Consumption of anti-bacterial agents and resistance rate of Pseudomonas aeruginosa in respiratory unit |
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| YANG Xin-yun,XIAO Xiang-lin,CHEN Wen-ying,YUAN Jin-Ping,YANG Ling.Analysis of the correlation between Consumption of anti-bacterial agents and resistance rate of Pseudomonas aeruginosa in respiratory unit[J].Strait Pharmaceutical Journal,2007,19(6):108-110. |
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| Authors: | YANG Xin-yun XIAO Xiang-lin CHEN Wen-ying YUAN Jin-Ping YANG Ling |
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| Institution: | 1. The First Affiliated Hospital of Guangzhou Medical College, Guangzhou .5]0]20, China;2. Guangzhou Institute of Respiratory Disease,Guangzhou .510120, China |
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| Abstract: | OBJECTIVE To investigate the relationship between administration of anti-bacterial agents and resistance rate of P.aeruginosa in respiratory unit.METHODS The total anti-bacterial consumption expressed as defined daily doses(DDD)/day/100bed,as well as resistance rate of P.aeruginosa were collected,and their correlation was analyzed.RESULTS The analysis revealed a significant positive correlation between the consumption of Cefepime and Cefoperazone-Sulbactam and Meropenem between resistance rate of P.aeruginosa of Ciprofloxacin and Levofloxacin and Ceftazidime,respectively.The analysis revealed a significant positive correlation between the consumption of Levofloxacin between resistance rate of P.aeruginosa of Cefoperazone-Sulbactam and Imipenem.CONCLUSION The correlation between the consumption of anti-bacterial agents and resistance rate of Pseudomonas aeruginosa revealed an association in respiratory unit. |
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| Keywords: | Pseudomonas aeruginosa Drug resistance Consumption of anti-bacterial agents |
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