儿泻停颗粒联合蒙脱石散剂治疗小儿急性腹泻疗效评价

目的：探究儿泻停颗粒联合蒙脱石散剂治疗小儿急性腹泻的临床疗效及安全性，为临床用药提供参考依据。方法研究对象为随机选取为2014年1月—2015年1月之间该院收治的100例急性腹泻患儿，采用数字表法随机分为研究组和对照组各50例，两组患儿均给予相同的常规治疗措施，对照组采用蒙脱石散治疗，研究组则采用儿泻停颗粒联合蒙脱石散治疗，对比两组患儿的疗效、症状改善时间及用药不良反应。结果研究组患儿的总有效率为98.0%，显著高于对照组的78.0%，差异有统计学意义(P﹤0.05)；研究组患儿的体温恢复时间、呕吐、腹痛、腹泻消失时间均显著低于对照组，差异有统计学意义(P﹤0.05)；两组患儿治疗期间各有2例出现轻度便秘现象，无其他不良反应发生(P﹥0.05)。结论儿泻停颗粒联合蒙脱石散治疗小儿急性腹泻的疗效显著，相较于单纯采用蒙脱石散治疗能够提高疗效，迅速改善症状，且安全性较好，值得在临床上推广和应用。

Curative Evaluation on Infants Diarrhea Stopping Granule Combined with Montmorillonite Powder in Treatment of Children with Acute Diarrhea

Objective To study the clinical curative effect and security of infants diarrhea stopping granule combined with montmorillonite powder in treatment of children with acute diarrhea and provide reference for clinical drug uses. Methods 100 cases of children with acute diarrhea treated in our hospital from January 2014 to January 2015 were selected as the research object and randomly divided into two groups with 50 cases in each, the two groups were given the same conven-tional treatment measures, the control group were treated with montmorillonite powder, the research group were treated with infants diarrhea stopping granule combined with montmorillonite powder, the curative effect, symptom improvement time and adverse drug reaction of the two groups were compared. Results The total effective rate in the research group was obviously higher than that in the control group (98.0%vs 78.0%), the difference was statistically significant (P﹤0.05);the body tem-perature recovery time, vomiting, stomachache and diarrhea disappearance time in the research group were obviously lower than those in the control group , the differences were statistically significant (P﹤0.05), each group has 2 cases with mild constipation phenomenon during treatment, there was no other adverse reaction (P﹥0.05). Conclusion Infants diarrhea stopping granule combined with montmorillonite powder in treatment of children with acute diarrhea has an obvious curative effect, and it can improve the curative effect and improve the symptoms quickly compared with simple montmorillonite pow-der treatment, and it has good security and is worthy of promotion and application in clinic.