血清CEA、CA19—9、CA724检测对老年胃癌病理、临床分期的意义

目的：探讨血清CEA、CA19—9、CA724对老年胃癌的临床应用价值。方法：采用ELISA方法对87例老年胃癌患者进行回顾性分析。结果：老年胃癌患者CEA、CA19—9、CA724阳性率分别为25％、21％、21％，联合检测阳性率为41％，其中TNMIV期患者CA19—9、CA724、联合检测阳性率明显高于TNMⅠ＋Ⅱ期患者。TNMⅢ＋Ⅳ期患者CA19—9、CA724检测值明显高于Ⅰ＋Ⅱ期患者。CEA、CA19—9、CA724阳性率、其值大小与胃癌病理类型、分化无关。结论：CEA、CA19—9、CA724可用于老年胃癌的诊断、病情判断，联合检测可提高诊断效率，但早期诊断价值有限。

The clinical analysis of serum CEA, CA19 -9 and CA724 in elderly patients with gastric carcinoma

Objective：To investigate the clinical application value of serum CEA, CA19 -9 and CA724 in elderly patients with gastric carcinoma. Methods：To analyse data of 87 elderly patients by using ELISA method. Results：The positive rates of CEA, CA19 -9 and CA724 were 25% ,21% ,21% respectively, and the positive rate of CEA, CA19 -9 and CA724 combination test was 41%. The positive rate of CA19 -9, CA724 and combination test in TNM stage IV patients was higher than that in TNM stage Ⅰ and Ⅱ patients. The value of CA19 -9 and CA724 in TNM stage Ⅲ and Ⅳ patients was higher than that in TNM stage Ⅰ and Ⅱ patients. The positive rate and value of tumor markers were not related to tumor pathological type and differentiation. Conclusion： CEA, CA19 -9 and CA724 can be used for diagnosis of gastric carcinoma and judgement of elderly patient＇s condition. CEA, CA19 -9 and CA724 combined examination can increase diagnostic efficiency. But They have only limited diagnostic usefulness in elderly patients with early gastric carcinoma.