2012 - 2018年烟台市心脑血管急性事件流行趋势及疾病负担分析

目的 探讨烟台市2012 - 2018年心脑血管急性事件的发病死亡流行趋势以及疾病负担，为制定本地化的心脑血管疾病防控策略提供依据。方法 对烟台市2012 - 2018年的心脑血管急性事件统计资料进行分析，运用Joinpoint回归计算心脑血管急性事件的发病和死亡流行趋势，采用WHO推荐的疾病负担分析方法，计算心脑血管急性事件的伤残调整生命年（DALYs）。结果 烟台市2012 - 2018年心脑血管急性事件的年均报告发病率546.40/10万（标化发病率273.56/10万），年均报告死亡率232.93/10万（标化死亡率104.76/10万），发病率及标化发病率呈逐年上升的趋势，APC分别为11.55%和9.25%；死亡率及标化死亡率呈逐年下降趋势，APC分别为 - 1.82%和 - 6.34%。烟台市脑卒中的DALYs强度为17.35人年/千人，冠心病急性事件的DALYs强度为11.51人年/千人，二者死亡负担所占比例均大于失能负担，且男性DALYs强度均高于女性。60岁以后均明显增加，并随着年龄的增加而加重。结论 烟台市的心脑血管疾病防控形势仍然很严峻，应进一步探索更加科学有效和适合烟台当地特点的防控策略。

Epidemic trends and disease burden of acute cardiovascular and cerebrovascular events in Yantai city from 2012 to 2018

To explore the epidemic trend and disease burden of cardiovascular and cerebrovascular acute events in Yantai City from 2012 to 2018, and to provide a basis for the development of prevention and control strategy for local cardiovascular and cerebrovascular disease. Methods The statistical data of cardiovascular and cerebrovascular acute events in Yantai City from 2012 to 2018 were analyzed, and Join point regression was used to calculate the epidemic trend of cardiovascular events and deaths. WHO recommended disease burden analysis was used to calculate disability adjusted life years (DALYs) of acute cardiovascular and cerebrovascular events. Results The average annual incidence rate of cardiovascular and cerebrovascular events in Yantai City from 2012 to 2018 was 546.40/100000 (standardized incidence rate of 273.56/100000), and the annual average mortality rate was 232.93/100000 (standardized mortality rate of 104.76/100000). The incidence and age-adjusted incidence of acute cardiovascular and cerebrovascular events in Yantai City increased year by year from 2012 to 2018, and APC was equal to 11.55% and 9.25% , respectively. The mortality rate and age -adjusted mortality rate decreased year by year, and APC was equal to -1.82% and -6.34% , respectively. The DALYs intensity of cerebral apoplexy in Yantai City was 17.35 person-years/1000 people, and the intensity of DALYs for acute coronary events was 11.51 person-years/1000 people. Both of the burden of death was greater than the burden of disability and both of the intensity of DALYs was higher in men than that in women. After the age of 60, the burden of death and disability increased obviously and aggravated with the increase of age. Conclusion The prevention and control situation of cardiovascular and cerebrovascular diseases in Yantai City is still very serious, and more scientific and effective prevention and control strategies suitable for Yantai’s local characteristics should be explored.