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融合CNN和BiLSTM的心律失常心拍分类模型
引用本文:杨浩,黄茂林,蔡志鹏,姚映佳,李建清,刘澄玉.融合CNN和BiLSTM的心律失常心拍分类模型[J].中国生物医学工程学报,2020,39(6):719-726.
作者姓名:杨浩  黄茂林  蔡志鹏  姚映佳  李建清  刘澄玉
作者单位:1(联想研究院,广东 深圳 518057)2(东南大学仪器科学与工程学院,南京 210096)
基金项目:国家自然科学基金(81871444);江苏省杰出青年基金(BK20190014);江苏省重点研发计划项目(BE2017735)
摘    要:为更加准确地从动态心电中提取异常心拍,设计一种融合卷积神经网络(CNN)和多层双边长短时记忆网络(BiLSTM)的心律失常心拍分类模型。心电信号首先被分割成0.75 s和4 s两种不同尺度大小的心拍信号,然后利用11层CNN网络和3层BiLSTM网络分别对小/大尺度心拍信号进行特征提取与合并,并使用3层全连接网络对合并特征进行降维,最后利用softmax函数实现分类。针对MIT心律失常数据库异常心拍类型分布不均衡的问题,采用添加随机运动噪声和基线漂移噪声的样本扩展方法,降低模型的过拟合。采用基于患者的5折交叉检验进行模型验证。MIT心律失常数据库116 000个心拍的分类结果表明:所建立的模型针对4类心拍(正常、房性早搏、室性早搏、未分类)的识别准确率为90.42%,比单独使用CNN(76.45%)和BiLSTM(83.28%)的模型分别提高13.97%和7.14%。所提出的融合CNN和BiLSTM的心律失常心拍分类模型,相比单一基于CNN模型或者BiLSTM模型的机器学习算法,有更好的异常心拍分类准确率。

关 键 词:心律失常  心拍分类  心电  卷积神经网络  双边长短时记忆网络  
收稿时间:2019-03-11

Arrhythmia Beat Classification Model Based on CNN and BiLSTM
Yang Hao,Huang Maolin,Cai Zhipeng,Yao Yingjia,Li Jianqing,Liu Chengyu.Arrhythmia Beat Classification Model Based on CNN and BiLSTM[J].Chinese Journal of Biomedical Engineering,2020,39(6):719-726.
Authors:Yang Hao  Huang Maolin  Cai Zhipeng  Yao Yingjia  Li Jianqing  Liu Chengyu
Institution:(Lenovo Research, Shenzhen 518057, Guangdong, China)(School of Instrument Science and Engineering, Southeast University, Nanjing 210096, China)
Abstract:In order to extract the abnormal beats more accurately from the dynamic electrocardiograph (ECG), a deep learning model combining convolutional neural network (CNN) and bi-directional long short-term memory network (BiLSTM) was proposed in this study. Firstly, ECG signals were segmented into two types of time window lengths: a small-scale length of 0.75 s and a large-scale length of 4 s. Then, features were extracted from the small- and large-scale length ECG segments using an 11-layer CNN network and a 3-layer BiLSTM network, respectively. Finally, the extracted features were combined and were then reduced using a 3-layer fully connected network. In addition, two data enhancement methods by adding random motion noise and baseline drift were used to attenuate the influence of over-fitting due to the unbalanced data distribution. The proposed model was tested on the MIT arrhythmia database using a patient-based 5-fold cross-validation method, and its accuracy for classifying the 4 types (normal, atrial premature, ventricular premature and unclassified) on 116,000 heartbeats was 90.42%, which was 13.97% and 7.14% higher than the CNN model (76.45%) and BiLSTM model (83.28%), respectively. This study validated that the proposed model with combining CNN and BiLSTM reports higher accuracy than only using CNN or BiLSTM model when performing the abnormal beat classification task.
Keywords:arrhythmia  beat classification  electrocardiograms (ECG)  convolutional neural network (CNN)  bi-directional long short-term memory network (BiLSTM)  
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