冠心病患者血清超敏C反应蛋白、肌钙蛋白、血脂水平的变化及临床意义

目的 探究冠心病患者血清超敏C反应蛋白（hs-CRP）、肌钙蛋白Ⅰ（cTnⅠ）、血脂水平的变化及临床意义。方法 选择2017年2月~2019年2月我院收治的80例冠心病患者作为研究对象，根据疾病类型分为稳定型心绞痛（SAP）组35例、急性心肌梗死（AMI）组20例及不稳定性心绞痛（UAP）组25例，另选取同期在我院进行体检的50例健康者作为对照组，比较四组hs-CRP、cTnⅠ、血脂水平（TC、TG、HDL-C、LDL-C）。结果 SAP、UAP、AMI组hs-CRP、cTnⅠ高于对照组，AMI组hs-CRP、cTnⅠ高于SAP组、UAP、SAP组hs-CRP、cTnⅠ高于SAP组，差异有统计学意义（P＜0.05）。SAP、UAP、AMI组TC、TG、LDL-C高于对照组，HDL-C低于对照组，差异有统计学意义（P＜0.05）；UAP、AMI组TC、TG、LDL-C低于SAP组，HDL-C高于SAP组，差异有统计学意义（P＜0.05）。结论 冠心病患者检测血清hs-CRP、cTnⅠ、血脂水平可有效预防疾病，对判断病情及评估预后有重要的临床意义。

Changes and Clinical Significance of Serum High-sensitivity C-reactive Protein,Troponin and Blood Lipid Levels in Patients with Coronary Heart Disease

Objective To investigate the changes of serum high-sensitivity C-reactive protein (hs-CRP), troponin Ⅰ (cTnⅠ), blood lipid levels and their clinical significance in patients with coronary heart disease. Methods 80 patients with coronary heart disease treated in our hospital from February 2017 to February 2019 were selected as the research subjects. According to the type of disease, they were divided into 35 patients with stable angina pectoris (SAP) group, 20 patients with acute myocardial infarction (AMI) group and 25 patients with unstable angina pectoris (UAP) group. Another 50 healthy people who underwent physical examination in our hospital during the same period were selected as the control group, and the hs-CRP, cTnⅠ, and lipid levels (TC, TG, HDL-C, LDL-C) of the four groups were compared.Results hs-CRP and cTnⅠof SAP group, UAP group and AMI group were higher than those of control group, hs-CRP and cTnI of AMI group were higher than those of SAP group and UAP group, hs-CRP and cTnⅠof SAP group were higher than SAP group, the difference was statistically significant (P<0.05).The TC, TG, and LDL-C in the SAP, UAP, and AMI groups were higher than those in the control group, and the HDL-C was lower than that in the control group, the differences were statistically significant (P<0.05); UAP group, AMI group TC, TG, LDL-C were lower than SAP group, HDL-C was higher than SAP group, the difference was statistically significant (P<0.05). Conclusion The detection of serum hs-CRP, cTnⅠ, and blood lipid levels in patients with coronary heart disease can effectively prevent the disease and has important clinical significance for judging the condition and assessing the prognosis.