| 阿帕替尼联合化疗治疗晚期胃癌:1例报告并文献复习 |
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| 引用本文： | 程弘敏,赵建夫,徐萌. 阿帕替尼联合化疗治疗晚期胃癌:1例报告并文献复习[J]. 分子影像学杂志, 2020, 43(3): 528-532. DOI: 10.12122/j.issn.1674-4500.2020.03.34 |
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| 作者姓名： | 程弘敏 赵建夫 徐萌 |
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| 作者单位： | 暨南大学附属第一医院肿瘤科,广东 广州 510630 |
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| 基金项目： | 国家自然科学基金（81672953）;广东省中医药科学技术研究项目（20182020） |
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| 摘 要： | 胃癌是常见的消化道肿瘤之一,目前早期胃癌可以通过外科手术根治。但由于胃癌早期诊断率低,大部分患者就诊时已是局部晚期或发生转移,主要治疗方式仍然是化疗。然而单纯化疗的疗效仍十分有限且已达到瓶颈。随着肿瘤分子生物学及免疫学的发展,分子靶向治疗及免疫治疗成为晚期胃癌患者带来新的希望。本文报道阿帕替尼联合化疗治疗晚期胃癌1例,为晚期胃癌的靶向联合化疗提供参考。
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| 关 键 词： | 晚期胃癌 阿帕替尼 化疗 免疫检查点抑制剂 |
| 收稿时间： | 2020-03-06 |
Apatinib combined with chemotherapy for advanced gastric cancer: A case report and literature review |
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| Hongmin CHENG,Jianfu ZHAO,Meng XU. Apatinib combined with chemotherapy for advanced gastric cancer: A case report and literature review[J]. Journal of Molecular Imaging, 2020, 43(3): 528-532. DOI: 10.12122/j.issn.1674-4500.2020.03.34 |
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| Authors: | Hongmin CHENG Jianfu ZHAO Meng XU |
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| Affiliation: | Department of Oncology, the First Affiliated Hospital of Jinan University, Guangzhou 510630, China |
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| Abstract: | Gastric cancer is one of the common digestive tract tumors. Early gastric cancer can be cured by surgery. However, due to the low early diagnosis rate of gastric cancer, most patients have local advanced or metastasis at the time of treatment. The main treatment of advanced gastric cancer is still chemotherapy. The efficacy of chemotherapy alone is limited. With the development of tumor molecular biology and immunology, molecular targeted therapy and immunotherapy have brought new hope for patients with advanced gastric cancer. This article reports one case of apatinib combined with chemotherapy for advanced gastric cancer, providing a reference for targeted combined chemotherapy for advanced gastric cancer. |
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