T2WI、DWI及DCE-MRI联合诊断前列腺癌的效果分析

目的:探讨T2加权成像（T2WI）、扩散加权成像（DWI）及动态对比增强磁共振成像（DCE-MRI）联合诊断前列腺癌的价值。方法:选取2017年3月—2019年4月就诊的疑似前列腺癌患者119例，均行常规MRI、DWI和DCE-MRI检查。结果:119例疑似患者中，有69例诊断为前列腺癌，有50例诊断为前列腺增生；T2WI、DWI和DCE-MRI联合诊断前列腺癌的灵敏性为97.10%，明显高于T2WI、DWI单独诊断（均P＜0.05）；T2WI、DWI、DCE-MRI及联合诊断前列腺癌特异性、准确率比较差异无统计学意义（均P＞0.05）；前列腺癌Ktrans、KeP、Ve和VP分别为（1.42±0.87）、（1.83±0.80）、（0.84±0.21）和（0.15±0.07），明显高于前列腺增生（均P＜0.05），而ADC为（0.92±0.34）×10-3 mm2/s，明显低于前列腺增生（P＜0.05）；Ktrans、KeP、Ve、VP与Gleason评分无相关性（均P＞0.05），ADC值与Gleason评分呈负相关（r=-0.508，P＜0.05）。结论:T2WI、DWI及DCE-MRI联合用于诊断前列腺癌有较好的效果，其中DWI及DCE-MRI可为诊断提供客观参数。

Efficacy of combined use of T2WI,DWI and DCE-MRI in the diagnosis of prostate cancer

Objective: To explore the value of combined use of T2-weighted imaging(T2WI), diffusion-weighted imaging(DWI) and dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) in the diagnosis of prostate cancer. Methods: 119 patients with suspected prostate cancer were selected from March 2017 to April 2019, and the routine MRI, DWI and DCE-MRI were performed. Results: Of 119 suspected cases, 69 were diagnosed as prostate cancer and 50 were diagnosed as benign prostatic hyperplasia. The sensitivity of combined diagnosis of T2WI, DWI and DCE-MRI for prostate cancer was 97.10%, which were significantly higher than that of single diagnosis of T2WI and DWI (all P< 0.05). There were no significant difference in specificity and accuracy of T2WI, DWI, DCE-MRI and combined diagnosis of prostate cancer (all P> 0.05). Ktrans, KeP, Ve and VP of prostate cancer were (1.42±0.87), (1.83±0.80), (0.84±0.21) and (0.15±0.07) respectively, which were significantly higher than those of benign prostatic hyperplasia (all P<0.05), while ADC was (0.92±0.34)×10-3 mm2/s, which was significantly lower than that of benign prostatic hyperplasia(P< 0.05). Ktrans, KeP, Ve and VP were not correlated with Gleason score(all P>0.05), but ADC was negatively correlated with Gleason score(r=-0.508, P<0.05). Conclusion: The combination of T2WI, DWI and DCE-MRI has a good effect in the diagnosis of prostate cancer, and DWI and DCE-MRI can provide objective parameters for the diagnosis.