活血化瘀汤治疗急性心肌梗死伴心房颤动临床研究

目的:探讨活血化瘀汤对急性心肌梗死伴心房颤动患者的临床改善作用。方法:选取急性心肌梗死伴心房颤动患者72例,分为两组,对照组应用常规治疗,研究组应用活血化瘀汤治疗。比较两组各项指标改善情况、整体疗效、不良反应发生率、心功能、血清炎性细胞因子IL-10、血黏附因子。结果:研究组总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)均低于对照组(P<0.05),高密度脂蛋白胆固醇(HDL-C)高于对照组(P<0.05); 研究组整体疗效优于对照组(P<0.05); 研究组房室传导阻滞、心动过缓、窦性停搏、恶心呕吐情况均少于对照组(P<0.05); 研究组心排血量(CO)、左心室射血分数(LVEF)高于对照组(P<0.05),左心室收缩末内径(LVESD)、左心室舒张末内径(LVEDD)低于对照组(P<0.05); 研究组IL-10、血黏附因子均低于对照组(P<0.05)。结论:急性心肌梗死伴心房颤动患者的治疗过程当中,活血化瘀汤治疗效果较好,可以改善患者临床症状。

Effect of Huoxue Huayu decoction in the treatment of acute myocardial infarction and atrial fibrillation

Objective:To investigate the effect of Huoxue Huayu decoction on TC,TG,HDL-C and LDL-C in patients with acute myocardial infarction and atrial fibrillation.Methods:72 patients with acute myocardial infarction and atrial fibrillation were divided into two groups according to different treatment methods.The control group was treated with routine treatment,and the study group was treated with Huoxue Huayu decoction.The improvement of each index,the overall efficacy,the probability of adverse reactions,cardiac function,serum cytokine IL-10 and blood adhesion factor were compared between the two groups.Results:TC,TG and LDL-C in the study group were lower than those in the control group,IL-10 and blood adhesion factor in the study group were lower than those in the control group(P<0.05).Conclusion:In the treatment of patients with acute myocardial infarction and atrial fibrillation,the effect of Huoxue Huayu decoction is ideal,and should be further applied in clinical practice.