超声造影评价膳食炎症指数与颈动脉斑块内增强特征的相关性

目的探讨超声造影对膳食炎症指数（DII）与颈动脉斑块内增强特征的相关性。方法选取2015年3月~2019年10月在我院行颈动脉斑块复查的77例患者作为研究对象。采用食物频率问卷表调查患者的日常饮食数据，应用膳食营养软件计算食物的膳食成分/营养素的DII指数。根据患者DII指数分组，即DII指数为正数纳入促炎饮食组（n=35），DII指数为负数纳入抗炎饮食组（n=42）；并根据患者DII指数划分5个等级，即≤-1.05、-1.05~-0.33、-0.33~0.38、0.38~1.22、≥1.22。采用彩色多普勒超声检测患者颈动脉斑块，对其斑块厚度、回声类型、斑块造影剂分布特征进行分析。双变量相关性分析采用Kendall相关系数法检验。结果促炎饮食组35例患者共41枚斑块，抗炎饮食组42例患者共47枚斑块。促炎饮食组的斑块厚度较抗炎饮食组的增厚，差异有统计学意义（P < 0.05）；促炎饮食组超声造影增强多于抗炎饮食组，差异有统计学意义（P < 0.05）。DII指数与颈动脉斑块内膜有无增强呈显著性正相关（Kendall相关系数为0.659，P < 0.001）。结论促炎饮食患者的颈动脉斑块较厚，DII指数越高，颈动脉斑块斑块内增强特征越明显。 

Correlation of dietary inflammatory index and carotid plaque enhancement by contrastenhanced ultrasonography

ObjectiveTo explore the correlation between dietary inflammatory index (DII) and enhancement characteristics of carotid plaque by contrast-enhanced ultrasound.MethodsFrom March 2015 to October 2019, 77 patients with carotid plaque reexamined in our hospital were selected as the study objects. Food frequency questionnaire was used to collect the data of patients' daily diet, The DiI index of dietary components/nutrients of food was calculated by dietary nutrition software. According to the DiI index of patients, the positive DiI index (35 cases) was included in the anti-inflammatory diet group, and the negative DiI index (42 cases) was included in the anti-inflammatory diet group. According to the DiI index of patients, 5 grades were divided, That is ≤-1.05, -1.05~-0.33, -0.33~0.38, 0.38~ < 1.22 and ≥1.22. Carotid plaque was detected by color Doppler ultrasound. The plaque thickness, echo type and the distribution of plaque contrast agent were analyzed. Kendall correlation coefficient method was used to test the bivariate correlation analysis.ResultsThere were 41 plaques in 35 patients in the pro-inflammatory diet group and 47 plaques in 42 patients in the anti-inflammatory diet group. Inflammation promoting diet group of plaque thickness relatively anti-inflammatory diet group of thickening. The difference was statistically significant (P < 0.05). Inflammation promoting diet group contrast enhanced ultrasound enhance many to antiinflammatory diet group. The difference was statistically significant (P < 0.05). There was a significant positive correlation between DiI index and carotid plaque intima enhancement (Kendall correlation coefficient 0.659, P < 0.001).ConclusionsCarotid plaques are quite thick in patients with pro-inflammatory diet. The higher the DiI index, the more obvious the enhancement characteristics of carotid plaque.