颈动脉粥样硬化与缺血性脑血管病的相关性研究及危险因素分析

目的 探讨颈动脉粥样硬化与缺血性脑血管病的相关性,并针对相关危险因素进行分析。方法 回顾性分析我院缺血性脑血管病的住院患者80例和同期健康体检者80例,分别为观察组和对照组,记录两组的血清胱抑素C(CysC)、甘油三酯(TG)、血清总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平、两侧颈动脉内径及颈动脉内-中膜厚度(IMT),应用SPSS 19.0进行统计学分析,对以上因素进行Logistic回归分析。结果 两组患者的CysC、TC、HDL-C、两侧IMT值差异有统计学意义,P＜0.05;Logistic回归分析结果显示,CysC、HDL-C、两侧IMT与缺血性脑血管病存在相关性;观察组的CysC和两侧颈动脉IMT水平高于对照组,HDL-C水平低于对照组(P＜0.05)。结论 颈动脉IMT与缺血性脑血管病有相关性,CysC的升高和HDL-C的降低是其发病的危险因素。

Correlation between carotid atherosclerosis and ischemic cerebrovascular disease and the analysis of risk factors

Objective To explore the correlation between carotid atherosclerosis and ischemic cerebrovascular disease and analyze the risk factors.Methods Eighty hospitalized patients with ischemic cerebrovascular disease and 80 healthy people with check-up were retrospectively analyzed,and were taken as the observation group and the control group respectively.The records were set down in the two groups of urinary inhibition C (CysC),serum triglyceride (TG),serum total cholesterol (TC),high-density lipoprotein cholesterol (HDL-C),low density lipoprotein cholesterol (LDL-C) levels,the carotid artery diameter on both sides and film thickness (IMT) in the carotid artery.SPSS19.0 was used for statistical analysis and logistic regression analysis was carried out on the above factors.Results The differences of CysC,TC,HDL-C and IMT values between the two groups were statistically significant (P<0.05).Logistic regression analysis showed that CysC,HDL-C and bilateral IMT were correlated with ischemic cerebrovascular disease.The levels of CysC and bilateral carotid ARTERY IMT in the observation group were higher than those in the control group,and hdL-C level was lower than that in the control group (P<0.05).Conclusion Carotid internal-media thickness (IMT) is associated with ischemic cerebrovascular disease,while the increase of CysC and the decrease of HDL-C are the risk factors.