痛风性膝关节炎关节软骨T2值与软骨损伤的相关性

目的：比较痛风性膝关节炎患者和健康志愿者膝关节软骨的T2值，探讨膝关节软骨的T2值与关节软骨损伤程度的相关性。方法：收集经临床确诊痛风性膝关节炎患者47例共56个膝关节作为病例组；无膝关节疾病的健康志愿者15 例共30 个膝关节作为对照组。两名放射科医师依据国际软骨修复协会（ICRS）分级标准对膝关节常规序列上痛风的表现和关节软骨损伤分级进行评估，将ICRS I-II级划为轻度软骨损伤，III-IV级划为重度软骨损伤。分别测量髌骨、股骨滑车、股骨内侧髁、股骨外侧髁、内侧胫骨平台、外侧胫骨平台的软骨T2值，比较病例组关节软骨T2值与对照组的差异，并对组间和组内进行一致性验证。结果：病例组膝关节各部位测量的软骨T2 平均值均显著高于对照组（P ＜0.05）；组间和组内一致性均较好。结论：痛风性膝关节炎患者关节软骨的T2值明显高于健康者。

Correlation analysis of T2 value of articular cartilage and cartilage injury in gouty knee arthritis

Objective: To explore the correlation between T2 value of the knee joint cartilage and the degree of articular cartilage damage through a comparative study of patients with gouty arthritis and healthy volunteers.Methods: A total of 47 patients who were clinically diagnosed with gouty knee arthritis (56 cases) were selected as the case group, and 15 healthy volunteers (30 cases) without knee disease were assigned to the control group.According to the ICRs grading standard, two radiologists evaluated the performance of gout and the grading of articular cartilage injury on the conventional sequence of the knee joint. The ICRs I-II grade was classified as mild and the ICRs III-IV grade as severe cartilage injury. The cartilage T2 values of patella (patella), femoral trochlear (FT), medial femoral condyle (MFC), lateral femoral condyle (LFC), medial tibial plateau (MTP) and lateral tibial plateau (LTP) were measured respectively. The difference in T2 values between gouty knee arthritis patients and normal control group was compared, and the consistency between the two groups was verified.Results: The average value of cartilage T2 measured in all parts of the knee joint was significantly higher than that in the control group (P<0.05); the consistency between groups and within groups was good. Conclusion:The T2 value of articular cartilage in patients with gouty knee arthritis was significantly higher than that in the control group.