2015 - 2017年四川省疾病负担研究

目的 分析四川省疾病负担现状，为制定疾病防控策略提供可靠的科学依据。方法 收集2015 - 2017年四川省死因监测数据，计算伤残调整寿命年(disability - adjusted life, DALY)、早逝寿命损失年(years of life lost, YLL)和伤残寿命损失年(years lived with disability, YLD)来评估疾病负担水平。结果 2015 - 2017年四川省疾病负担DALY率为90.87‰，其中YLL率和YLD率分别为47.06‰和43.81‰。DALY率男性（106.55‰）高于女性（75.05‰）。疾病负担模式主要是以非传染性疾病为主（80%～85%）。前5位疾病负担为恶性肿瘤、心脑血管疾病、呼吸系统疾病、神经系统和精神障碍疾病、损伤，男性和女性DALY率分别占其总负担的75.44%和74.49%。5岁以下儿童疾病负担最重的为损伤（DALY率男19.81‰，女12.57‰）。5岁以后疾病负担随着年龄的增长不断增加，15～29岁神经系统和精神障碍疾病负担最重（DALY率男30.00‰，女36.61‰）；45岁以后疾病负担主要来自心脑血管疾病、呼吸系统疾病和恶性肿瘤，DALY率负担占其年龄段总负担的59%～77%。结论 四川省居民疾病负担仍较重且随着年龄增长不断增加，男性和老年人是疾病负担防控的重点人群。30岁以前重点防控疾病为损伤和神经系统和精神障碍疾病，45岁以后重点为心脑血管疾病、呼吸系统疾病和恶性肿瘤。

Study on the burden of disease in Sichuan Province between 2015 and 2017

To analysis the burden of diseases in Sichuan Province and provide scientific evidence for effective prevention and control of diseases. Methods Monitoring data of causes of death in Sichuan from 2015 to 2017 were collected.Disability-adjusted life year(DALY), years of life lost(YLL) and years lived with disability(YLD) were used to analyzed the burden of disease. Results From 2015 to 2017, the DALY rate of disease burden in Sichuan was 90.87‰, among which the YLL rate and YLD rate were 47.06‰ and 43.81‰, respectively. The DALY rate of male(106.55‰) was higher than that of female(75.05‰). The disease burden pattern is dominated by non-communicable diseases(80% to 85%). The top five disease burdens were malignant tumors, cardiovascular and cerebrovascular diseases, respiratory system diseases, nervous system and mental disorders, and injuries. The DALY rate of male and female accounted for 75.44% and 74.49% of the total burden respectively. The most serious disease burden of children under 5 years old was injury(male 19.81 ‰, female 12.57 ‰). The burden of disease after the age of 5 increases with the increase of age. The burden of nervous system and mental disorders was the most serious in 15-29 years old(male 30.00 ‰, female 36.61 ‰). The burden of disease after the age of 45 mainly comes from cardiovascular and cerebrovascular diseases, respiratory system diseases and malignant tumors, the burden of DALY rate accounted for 59%-77% of the total burden of the age group. Conclusion The disease burden of Sichuan residents is still heavy and increases with age. Men and the elderly are the key groups of disease burden prevention and control. Before the age of 30,the key prevention and control diseases were injury and nervous system and mental disorders, and after 45 years old, the focus was on cardiovascular and cerebrovascular diseases, respiratory system diseases and malignant tumors.