高龄产妇妊娠风险的回顾性分析

目的 为加强高龄产妇孕期保健、改善妊娠结局提供科学的依据。方法 收集≥35岁的高龄组病例2 994例,和同期住院分娩的适龄组16 172例,对比分析两组产妇的病历资料。结果 高龄组妊娠期糖尿病、前置胎盘、胎盘早剥等妊娠合并症或并发症明显高于适龄组(P＜0.05);高龄组胎儿生长受限、胎儿畸形等围生儿不良结局发生率均高于适龄组(P＜0.01);高龄组干预性早产比适龄组干预性早产发生率高(P<0.01)。结论 高龄妊娠母婴不良妊娠结局多,应加强高龄产妇围产期保健以降低合并症和远期并发症的发生率,保障母婴安全健康,应提倡适龄妊娠。

Retrospective analysis of pregnancy risk in the advanced maternal age

Objective To provide a scientific basis for strengthening the health care of high-age women during pregnancy and improving pregnancy outcome. Methods Totally 2 994 cases in the advanced maternal age group≥35 years and 16 172 cases in child-bearing age pregnancy at the same time of inpatient delivery were collected, and the medical records of the two groups were compared and analyzed. Results The complications of gestational diabetes mellitus, preplacental placenta and placental abruption in the advanced maternal age group were significantly higher than those in the child-bearing age group (P<0.05), and the incidences of adverse outcomes such as fetal growth restriction and fetal malformation in the advanced maternal age group was significantly higher than those in the child-bearing age group (P<0.01). The incidence of intervention preterm delivery in the advanced maternal age group was higher than that in the child-bearing age group (P<0.01). Conclusion In order to reduce the incidence of comorbidities and long-term complications, to ensure the safety and health of mothers and infants, we should promote appropriate age pregnancy.