超声引导肌肉注射A型肉毒毒素治疗脑卒中后上肢痉挛

目的 探讨超声引导肌肉注射A型肉毒毒素（botulinum toxin-A，BTX-A）治疗脑卒中后上肢痉挛的效果。 方法 将60例脑卒中患者随机分为两组，各30例，对照组行常规康复疗法，观察组行超声引导肌肉注射BTX-A治疗，比较两组治疗效果。 结果 治疗4周后观察组的改良Ashworth量表评分、痉挛指数、上肢运动功能评分、主动关节活动度、剪切模量、肌纤维厚度、肌纤维长度优于对照组（P＜0.05）。 结论 超声引导肌肉注射BTX-A治疗能明显改善患者上肢痉挛状态，值得临床推广。

Ultrasound guidance combined with botulinum toxin type A in the treatment of post-stroke upper limb spasticity

Objective To investigate the curative effect of ultrasound guidance combined with botulinum toxin type A(BTX-A) injection on post-stroke upper limb spasticity.Methods Sixty stroke patients were randomly divided into two groups, with 30 cases in each group. The control group received conventional rehabilitation therapy, while the observation group received ultrasound guidance combined with BTX-A injection. Therapeutic effects of the two groups were compared.Results At 4 weeks after treatment, the modified Ashworth scale(MAS) scores, clinic spasticity index(CSI) scores, Fugl-Meyer assessment scale(FMA) scores, initiative joint range of motion(AROM), modulus of rigidity(G), muscular thickness(MT) and fiber length(FL) of the observation group were better than those of the control group(P＜0.05).Conclusion Ultrasound guidance combined with BTX-A injection can significantly relieve upper limb spasticity, which, therefore, is worthy of clinical popularization.