厦门市2013-2018年围产儿出生缺陷监测情况分析

目的 分析厦门市围产儿出生缺陷发生情况及主要特征分布情况。方法 监测2013年1月1日至2018年12月31日厦门市34所开展助产技术服务的医疗机构出生的孕28周至生后7天的所有围产儿的出生缺陷情况。结果 2013-2018年厦门34所开展助产技术服务的医疗机构共住院分娩围产儿481262名，出生缺陷总发生率为129.97/万，出生缺陷发生率逐年提高。前5位出生缺陷类型为先天性心脏病(41.00/万)、多指（趾）(18.53/万)、耳畸形(7.58/万)、并指（趾）(5.57/万)、尿道下裂(4.68/万)。男性出生缺陷发生率(148.12/万)高于女性(107.39/万)（P＜0.001），出生缺陷发生率呈现随产妇年龄增大而逐渐升高的趋势（P＜0.001）。城镇产妇所生围产儿出生缺陷总发生率(179.21/万)高于乡村(78.09/万)（P＜0.001）。结论 厦门市出生缺陷发生率低于全国水平，但近几年呈现逐年升高的趋势，出生缺陷存在性别、年龄、城乡差异。

Surveillance on congenital abnormalities of prenatal infants in Xiamen, 2013-2018

To monitor and analyze the incidence and epidemiological characteristics of perinatal congenitalabnormalities in Xiamen.Methods Surveillance data on congenital abnormalities occurred among perinatal infants bornbetween 2013 to 2018 in 34 midwifery hospitals in Xiamen were analyzed.Ｒesults The total of 481262 perinatal infants wereborn in these 34 midwifery hospitals，from Jan 1st 2013 to Dec 31 2018.The total incidence of perinatal congenitalabnormalities in Xiamen was 129.97/10 000，showed an increasing trend year by year.The top five common types of congenitalabnormalities were congenital heart disease(41.00/10 000)，polydactyly(18.53/10 000)，ear deformity(7.58/10 000)，syndactyly(5.57/10 000)，hypospadias(4.68/10 000).The incidence of congenital abnormalities in male(148.12/10 000)was higher than female(107.39/10 000)(P＜0.001).The incidence of birth defects increased gradually with the increase ofmaternal age(P＜0.001).The incidence of urban mothers(179.21/10 000)was higher than that of rural mothers(78.09/10000)(P＜0.001).Conclusion Although the incidence of congenital abnormalities in Xiamen is lower than the nationallevel，it shows a trend of increasing year by year in recent years.There are gender，maternal age and urban－rural differences.