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Positron emission tomography in a patient with renal malacoplakia
Institution:1. Department of Pathology and Laboratory Medicine, University of Virginia Health Sciences Center, Charlottesville, VA, United States;2. Department of Pathology & Laboratory Medicine, Methodist Hospital, Houston, TX, United States;3. Department of Pathology, Baylor College of Medicine, Houston, TX, United States
Abstract:Positron emission tomography is increasingly used for the diagnosis of occult infection or malignancy. The altered metabolic rate of cells in areas of malignancy or infection provides a sensitive method to identify pathology that is otherwise not identified by standard imaging methods. This case report describes a patient who presented with a pyrexia of unknown origin and renal impairment. She had a positron emission tomography scan that showed intense accumulation of fluoro-deoxy-glucose in both kidneys. Subsequent renal biopsy results showed a diagnosis of malacoplakia, the treatment of which resulted in a resolution of the fever and a stabilization of renal function. This is the first report of the positron emission tomographic appearance of renal malacoplakia.
Keywords:Positron emission tomography (PET)  malacoplakia  pyrexia of unknown origin  renal failure
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