Assessment of muscle function in patients with COPD: preliminary results |
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| Affiliation: | 1. Laboratoire de physiologie de l''exercice musculaire et du sport, université Victor Segalen, Bordeaux 2, Carreire nord, bâtiment 2a, rdc, 146, rue Léo-Saignat, 33076 Bordeaux cedex, France;2. Service de réanimation médicale, Tripode Pellegrin, 33000 Bordeaux, France;1. Department of Adult and Pediatric Cardiovascular Surgery, University Hospital Giessen, Giessen, Germany;2. Institute of Physiology, Justus-Liebig University, Giessen, Germany;3. BHF/University of Edinburgh Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom;4. The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York;5. Marie-Josée and Henry R. Kravis Cardiovascular Health Center, Icahn School of Medicine at Mount Sinai, New York, New York;6. Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain;1. The Systems Life Sciences Laboratory, Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, 610-0394, Japan;2. Laboratory of Molecular Biology and Metabolism, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan;3. Department of Endocrinology and Metabolism, Kanazawa University Graduate School of Medical Sciences, Kanazawa, 920-8640, Japan;1. Department of Nutrition, The University of Nevada Reno, Reno, NV, 89557, USA;2. Cellular and Molecular Biology, The University of Nevada Reno, Reno, NV, 89557, USA;3. Center of Biomedical Research Excellence for Molecular and Cellular Signal Transduction in the Cardiovascular System, The University of Nevada Reno, Reno, NV, 89557, USA;1. Department of Health Sciences, Clinical Nutrition, College of Health and Rehabilitation Sciences, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia;2. Department of Biochemistry, College of Science, King Saud University, Riyadh, Saudi Arabia |
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| Abstract: | Aim. – To investigate muscle function during brief maximal sprint exercise in patients with chronic obstructive pulmonary disease (COPD).Materials and methods. – Eight patients underwent three tests: three maximal sprints on a specialised cycle ergometer to assess individual velocity–power relationship, anthropometric measurement, maximal oxygen uptake (VO2max).Results. – The maximal anaerobic power and corresponding optimal velocity were 3.9 ± 1.6 W kg–1 and 85.4 ± 17.0 rpm, respectively. COPD patients showed a 30% decrease in maximal anaerobic power, compared to healthy older subjects (5.6 ± 1.1 W kg–1). No such difference was observed in terms of optimal velocity. In addition, COPD patients showed a 43% lower VO2max compared to healthy older subjects (Eur. J. Appl. Physiol. 77 (1998) 182; Eur. J. Appl. Physiol. 76 (1997) 81).Conclusion. – The decrease in maximal anaerobic power was less than the decrease in maximal aerobic power. |
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