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心力衰竭患者标准药物治疗和心脏再同步化治疗结果分析
引用本文:邹卓群,汪芳.心力衰竭患者标准药物治疗和心脏再同步化治疗结果分析[J].中国心血管杂志,2011,16(3):201-204.
作者姓名:邹卓群  汪芳
作者单位:1. 上海交通大学附属第一人民医院危重病科,200080
2. 上海交通大学附属第一人民医院心内科,200080
摘    要:目的根据心脏再同步化用于心力衰竭(CARE-HF)研究结果 ,结合我国目前国情,探讨心力衰竭患者标准药物治疗和心脏再同步化治疗(CRT)联合有除颤功能的心脏再同步化治疗(CRTD)的长期结果。方法选择1999年12月至2008年4月行CRT、CRTD治疗的患者68例,为CRT/CRTD治疗组。选择同期常规药物治疗心力衰竭患者84例为对照组。所有入选患者,均需根据患者病情需要给予相应的药物治疗。结果 CRT/CRTD组患者生活质量较常规药物治疗组明显改善,但最终存活率差异无统计学意义76.5%(52/68)比73.8%(62/84),P>0.05]。但CRT/CRTD组中死于充血性心力衰竭的患者显著少于常规药物治疗组8.8%(6/68)比19.0%(16/84),P<0.05]。结论 CRT不能降低充血性心力衰竭患者的总体病死率,但在严重的充血性心力衰竭患者中,同时具备CRT和埋藏式心脏复律除颤器(ICD)的CRTD治疗可能成为最佳治疗方案。

关 键 词:心脏起搏  人工  心力衰竭  充血性  药物疗法

Comparison of standard medical therapy and CRT/CRT-D implantation on long term outcomes in patients with advanced congestive heart failure: a retrospective analysis
ZOU Zhao-qun,WANG Fang.Comparison of standard medical therapy and CRT/CRT-D implantation on long term outcomes in patients with advanced congestive heart failure: a retrospective analysis[J].Chinese Journal of Cardiovascular Medicine,2011,16(3):201-204.
Authors:ZOU Zhao-qun  WANG Fang
Institution:ZOU Zhuo-qun,WANG Fang.Intensive Care Unit,Shanghai First People's Hospital,Shanghai Jiao Tong University,Shanghai 200080,China
Abstract:Objective To investigate the long term outcomes of patients with advanced congestive heart failure (CHF) who accepted standard medical therapy or CRT/CRTD implantation.Methods Sixty-eight patients with advanced CHF who were implanted with a biventricular pacing system,ICD or CRTD were enrolled in this study as CRT/CRTD group.Eight-four patients with advanced CHF accepted standard medical therapy as control group.All patients were retrospectively interviewed and all cause mortality(primary outcome),quality o...
Keywords:Cardiac pacing  artificial  Heart failure  congestive  Drug therapy  
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