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| 咽炎颗粒的喷雾干燥工艺研究 | |
| 引用本文： | 王强,张沂,李华,肖小河,李会芳,凌云,胡燕君.咽炎颗粒的喷雾干燥工艺研究[J].解放军药学学报,2008,24(1):37-39. |
| 作者姓名： | 王强 张沂 李华 肖小河 李会芳 凌云 胡燕君 |
| 作者单位： | 1. 海军总医院,药剂科,北京,100037;军事医学科学院毒物药物研究所,北京,100850;解放军第302医院,全军中药研究所,北京,100039 2. 第三军医大学军职干休所,重庆,400037 3. 解放军第302医院,全军中药研究所,北京,100039 4. 总后勤部第一门诊部,药房,北京,100842 |
| 摘 要： | 目的确定咽炎颗粒喷雾干燥的最佳工艺。方法采用正交试验法，以含水量和蒙花苷含量为指标，考察进／出口风温、辅料加入量、浸膏相对密度3个因素对其的影响。结果咽炎颗粒喷雾干燥的最佳工艺条件为：进／出风温度160—165℃／80—85℃，辅料加入量40％，浸膏相对密度1．14。结论本试验为咽炎颗粒干燥工艺的改进提供了依据。 |
| 关 键 词： | 咽炎颗粒 喷雾干燥 制剂工艺 正交试验 |
| 文章编号： | 1008-9926(2008)01-0037-03 |
| 修稿时间： | 2007年7月23日 |
Study on Process for the Spray Drying of Yanyan Granules |
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| WANG Qiang,ZHANG Yi,LI Hua,XIAO Xiao-He,LI Hui-Fang,LING Yun,HU Yan-Jun.Study on Process for the Spray Drying of Yanyan Granules[J].Pharmaceutical Journal of Chinese People's Liberation Army,2008,24(1):37-39. | |
| Authors: | WANG Qiang ZHANG Yi LI Hua XIAO Xiao-He LI Hui-Fang LING Yun HU Yan-Jun |
| Institution: | WANG Qiang, ZHANG Yi, LI Hua, XIAO Xiao-He, LI Hui-Fang, LING Yun, HU Yan-Jun(1Department of Pharmacy, Navy General Hospital , Beijing 100037 China;2Academy of Military Medical Sciences of PLA, Beijing 100850 China;3China Institute of TCM,Hospital 302 of PLA, Beijing 100039 China;4The Third Military Medical University, Chongqing 400037 China;5Department of Pharmacy,The First Ambulant Clinic of GLD of PLA,Beijing 100842 China) |
| Abstract: | Aim To define the best process for spray drying of Yanyan granules. Methods The best process for spray drying of Yanyan granules was investigated by orthogonal experiments. Results The best process for spray drying of Yanyan granules involved an inlet-outlet temperature of 160 - 165℃/80 - 85℃, addition excipients of 40%, and relative density of extract of 1.14. Conclusions This investigation can provide reference for improvement of drying methods of Yanyan granules. |
| Keywords: | Yanyan Granules Spry drying Preparation technology Orthogonal experiment |
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