| 尿酸的表面增强拉曼光谱检验 |
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| 作者姓名： | Feng S Lin D Li Y Huang Z Wu Y Wang Y Lin J Chen R |
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| 作者单位： | 福建师范大学医学光电科学与技术教育部重点实验室,福建省光子技术重点实验室;福建省立医院 |
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| 基金项目： | 国家自然科学基金资助项目(11104030,61178090,81101110);福建省教育厅项目资助(JA11055) |
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| 摘 要： | 本文报道了以Ag纳米粒子作为增强基底的尿酸表面增强拉曼光谱(SERS)。文中测试了尿酸、银胶以及尿酸与银胶混合溶液的吸收光谱,探讨尿酸在银胶上可能的增强机制,并对所获得的尿酸溶液的SERS进行初步谱峰归属。同时还讨论了不同吸附时间、不同离子对尿酸增强效应的影响。本文尿酸在银胶中的检测限达到1mg/L。研究结果显示,尿酸溶液的SERS强度随浓度变化,因此,SERS可为尿酸定量检测提供一种直接、快速的新方法。
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| 关 键 词： | 表面增强拉曼光谱 银胶 尿酸 检测 |
Surface-enhanced Raman spectroscopic analysis of uric acid |
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| Feng S,Lin D,Li Y,Huang Z,Wu Y,Wang Y,Lin J,Chen R.Surface-enhanced Raman spectroscopic analysis of uric acid[J].Journal of Biomedical Engineering,2012,29(3):541-545. |
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| Authors: | Feng Shangyuan Lin Duo Li Yongzeng Huang Zufang Wu Yan'an Wang Yue Lin Juqiang Chen Rong |
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| Institution: | Key Laboratory of OptoElectronic Science and Technology for Medicine, Ministry of Education, Fujian Normal University, Fuzhou 350007, China. |
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| Abstract: | Based on Ag nanoparticles as the surface-enhanced Raman spectroscopy (SERS)-active nanostructure, the SERS of uric acid was presented in the paper. The absorption spectroscopies of uric acid and the mixture of silver colloids and uric acid were measured. The possible enhancing mechanism of the uric acid on silver colloid was speculated. The characteristic SERS bands of uric acid were tentatively assigned. The influence of absorption time and different ion on the SERS of uric acid were also discussed. The SERS spectral intensity changes linearly with the uric acid concentration, which indicated that the SERS might provide a new kind of direct and fast detecting method for the detection of uric acid. The detection limit of uric acid in silver sol is found to be 1 mg/L. |
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| Keywords: | Surface-enhanced Raman spectroscopy(SERS) Ag colloidal Uric acid Detection |
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