| 伏康树中生物碱化学成分研究 |
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| 引用本文： | Mei L,Deng Y,Li F,Guo DL,Lu CY. 伏康树中生物碱化学成分研究[J]. 中药材, 2012, 35(2): 226-229 |
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| 作者姓名： | Mei L Deng Y Li F Guo DL Lu CY |
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| 作者单位： | 成都中医药大学药学院中药材标准化教育部重点实验室/中药资源系统研究与开发利用省部共建国家重点实验室培育基地;中国科学院成都生物研究所 |
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| 基金项目： | 四川省杰出青年学术技术带头人资助计划(2010JQ0036) |
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| 摘 要： | 目的:研究伏康树中生物碱部分的化学成分。方法:采用正相硅胶、Sephadex LH-20等色谱方法进行分离纯化,并运用波谱分析的方法鉴定化合物结构。结果:分离并鉴定了8个生物碱类化合物,分别为:voacangine(1)、voacangine hydroxyindolenine(2)、19R-epi-voacristine(3)、epi-ibogaine(4)、vobasine(5)、19-epi-heyneanine(6)、vobtusine(7)和voacamine(8)。结论:其中,化合物2～4、6均为首次从该植物中分离得到。
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| 关 键 词： | 伏康树 生物碱 化学成分 |
Study on the alkaloids constituents from Voacanga africana |
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| Mei Ling,Deng Yun,Li Fu,Guo Da-le,Lu Chong-yu. Study on the alkaloids constituents from Voacanga africana[J]. Journal of Chinese medicinal materials, 2012, 35(2): 226-229 |
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| Authors: | Mei Ling Deng Yun Li Fu Guo Da-le Lu Chong-yu |
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| Affiliation: | Pharmaceutical College, Chengdu University of Traditional Chinese Medicine, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, State Key Laboratory Breeding Base of Systematic research, Development and Utilization of Chinese Medicine Resources, Chengdu 611137, China. Meilinger2011@hotmail.com |
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| Abstract: | Objective:To study the alkaloids of Voacanga africana.Methods:The alkaloids were isolated by normal phase silica gel and Sephadex LH-20 column chromatography.Their structures were elucidated by analysis of spectroscopic data.Results:Eight alkaloids were isolated and their structures were elucidated as voacangine(1),voacangine hydroxyindolenine(2),19R-epi-voacristine(3),epi-ibogaine(4),vobasine(5),19-epi-heyneanine(6),vobtusine(7) and voacamine(8).Conclusion:Compounds 2~4 and 6 are isolated from this plant for the first time. |
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| Keywords: | Voacanga africana Staph. Alkaloids Chemical constituents |
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