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| 妊娠早期人体胎盘中单胺氧化酶活性的测定 | |
| 引用本文： | 徐宏伟,杜卫,王秀丽,张爱青,张崇理. 妊娠早期人体胎盘中单胺氧化酶活性的测定[J]. 青岛大学医学院学报, 1999, 35(1): 41-42 |
| 作者姓名： | 徐宏伟 杜卫 王秀丽 张爱青 张崇理 |
| 作者单位： | 1. 青岛医学院生物化学教研室,青岛,266021 2. 青岛医学院附属医院妇产科 3. 中科院动物所计划生育生殖生物学国家重点实验室 |
| 基金项目： | 国家重点实验室基金，， |
| 摘 要： | 目的探讨妊娠早期人体胎盘中单胺氧化酶（ＭＡＯ－Ａ）活性与早期妊娠的关系。②方法应用分光光度法检测了妊娠５～９周人体胎盘绒毛中ＭＡＯ－Ａ活性。③结果随妊娠周数的增加，ＭＡＯ－Ａ活性增加。第８，９周胎盘绒毛中ＭＡＯ－Ａ活性明显高于第５周（Ｆ＝５．４４，ｑ＝３．７３，５．５４，Ｐ＜０．０５，０．０１）和第６周（ｑ＝３．０７，４．８３，Ｐ＜０．０５，０．０１）。其他各组间比较，差异无显著性（ｑ＝０．１０～２．６９，Ｐ＞０．０５）。④结论妊娠早期人体胎盘绒毛中ＭＡＯ－Ａ活性的变化，可能与妊娠过程神经递质或激素的合成和释放有关。 |
| 关 键 词： | 单胺氧化酶 胎盘绒毛 人 |
DETERMINATION OF MAO-A ACTIVITY IN HUMAN PLACENTA AT EARLY STAGE |
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| Xu Hongwei,Du Wei,Wang Xiuli,et al. DETERMINATION OF MAO-A ACTIVITY IN HUMAN PLACENTA AT EARLY STAGE[J]. Acta Academiae Medicinae Qingdao Universitatis, 1999, 35(1): 41-42 | |
| Authors: | Xu Hongwei Du Wei Wang Xiuli et al |
| Affiliation: | Xu Hongwei,Du Wei,Wang Xiuli,et al Department of Biochemistry,Qingdao Medical College,Qingdao 266021, |
| Abstract: | Objective To study the activity of MAOA in human placenta at early pregnant stage and its relationship with pregnancy. X]Methods Spectrophotometric method was performed to estimate the activity of MAOA in villous chorion of human placenta during 5th-9th pregnant weeks. Results The activity of MAOA increased along with the pregnant period. The activity of MAOA between 8th and 9th week was significantly higher than that of 5th week(F=5.44, q=3.73, 5.54, P<0.01) and 6th week(q=3.07, 4.83, P<0.05, 0.01). Conclusion MAOA existed in the villous chorion of human placenta. The changes of its activity was related to the biosynthesis and release of neurotransmitters or hormones during pregnancy.; |
| Keywords: | MAOA villous chorion of placenta human |
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