| 体外治疗性超声对大鼠纤溶系统的影响 |
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| 引用本文： | 王海清,曹林生,蒋小燕,李运锋.体外治疗性超声对大鼠纤溶系统的影响[J].心脑血管病防治,2003,3(2):18-19. |
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| 作者姓名： | 王海清 曹林生 蒋小燕 李运锋 |
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| 作者单位： | 1. 310014,浙江省人民医院心内科
2. 430022,华中科技大学同济医学院附属协和医院 |
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| 摘 要： | 目的 研究体外治疗性超声对大鼠血浆组织型纤溶酶原激活因子 (t-PA)、纤溶酶原激活物抑制因子 -1(PAI -1)的影响。方法 采用酶联免疫吸附法测定超声治疗前后大鼠血浆t-PA、PAI -1的改变。结果 超声治疗后ETUS组t-PA(0 .5 4± 0 .19)IU/ml,PAI -1(0 .44± 0 .18)AU/ml,对照组t -PA(0 .5 1± 0 .2 5 )IU/ml,PAI -1(0 .43± 0 .19)AU/ml,二者比较无明显差异 (P >0 .0 5 )。结论 治疗剂量超声对大鼠纤溶系统没有影响
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| 关 键 词： | 超声疗法 组织型纤溶酶原激活因子 纤溶酶原激活物抑制因子-1 大鼠 |
| 修稿时间： | 2003年1月23日 |
Effect of ETUS on plasma t-PA, PAI-1 in Rats |
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| Wang Haiqing,Cao Linsheng,Jiang Xiaoyan,et al..Effect of ETUS on plasma t-PA, PAI-1 in Rats[J].Prevention and Treatment of Cardio_Cerebral_Vascular Disease,2003,3(2):18-19. |
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| Authors: | Wang Haiqing Cao Linsheng Jiang Xiaoyan |
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| Institution: | Wang Haiqing,Cao Linsheng,Jiang Xiaoyan,et al. The Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China |
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| Abstract: | objective To study the effect of external therapeutic ultrasound (ETUS) on plasma tissue-type plasminogen activator (t-PA), PAI-1 in rats. Methods 46 rats were treated with ETUS (0.8MHz,2.1W/cm 2,lhr). Before and after treatment with ETUS, the levels of t-PA and PAI-1 were detected by ELISA. Results Before and after treatment with ETUS, the levels of t-PA and PAI-1 were not significantly changed ( P >0.05). Conclusions platelet activity was not changed by ETUS. |
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| Keywords: | External therapeutic ultrasound t-PA PAI-1 Rats |
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