Photodynamic therapy in vulvar intraepithelial neoplasia |
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Authors: | Olejek Anita Kozak-Darmas Iwona Biniszkiewicz Tomasz Kellas-Sleczka Sylwia Sieroń Aleksander |
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Affiliation: | Katedra i Oddzia? Kliniczny Ginekologii, Po?oznictwa i Ginekologii Onkologicznej SIUM w Bytomiu, Bytom. anitaolejek@wp.pl |
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Abstract: | INTRODUCTION: Vulvar intraepithelial neoplasia may lead to vulvar cancer. Vulvar cancer is a rare (accounting for about 2,5-5% of all malignant neoplasms), female genital organs cancer. Photodynamic therapy is a new treatment for a wide variety of malignancies and premalignant dysplasias. We wanted to examine the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VIN). DESIGN: The aim of the study was to analyze the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VIN). MATERIAL AND METHODS: We have analyzed 20 women with VIN, who were treated in our center - Clinic of Vulvar Diseases. All these women had photodynamic diagnosis (PDD), photodynamic therapy followed (PDT), with 5% ALA applied to the entire vulva. CONCLUSIONS: We have noted the reduction of subjective complaints, but the histopathological improvement was observed in fewer degree. |
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