| 北方农村地区居民常见慢性非传染性疾病的家系队列研究进展 |
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| 引用本文： | 王梦莹,唐迅,秦雪英,武轶群,李劲,高培,黄少平,李娜,杨冬立,任涛,吴涛,陈大方,胡永华. 北方农村地区居民常见慢性非传染性疾病的家系队列研究进展[J]. 中华流行病学杂志, 2018, 39(1): 94-97 |
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| 作者姓名： | 王梦莹 唐迅 秦雪英 武轶群 李劲 高培 黄少平 李娜 杨冬立 任涛 吴涛 陈大方 胡永华 |
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| 作者单位： | 100191 北京大学公共卫生学院流行病与卫生统计学系,100191 北京大学公共卫生学院流行病与卫生统计学系,100191 北京大学公共卫生学院流行病与卫生统计学系,100191 北京大学公共卫生学院流行病与卫生统计学系,100191 北京大学公共卫生学院流行病与卫生统计学系,100191 北京大学公共卫生学院流行病与卫生统计学系,102401 北京市房山区疾病预防控制中心办公室,102401 北京市房山区疾病预防控制中心办公室,102401 北京市房山区卫生局办公室,100191 北京大学公共卫生学院流行病与卫生统计学系,100191 北京大学公共卫生学院流行病与卫生统计学系,100191 北京大学公共卫生学院流行病与卫生统计学系,100191 北京大学公共卫生学院流行病与卫生统计学系 |
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| 基金项目： | 国家自然科学基金（81230066，81102177，81172744，81473043） |
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| 摘 要： | 家系队列研究是一种特殊的队列研究方法，以家系为单位收集研究对象的生物样本和环境暴露信息，并进行随访，为探索复杂性疾病病因研究中遗传、环境、基因-基因和基因-环境交互作用提供重要资源。本文将对“北方农村地区居民常见慢性非传染性疾病的家系队列研究”的目标、方法、初步结果、机遇与挑战进行简单介绍。
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| 关 键 词： | 高血压 脑卒中 糖尿病 家系队列研究 |
| 收稿时间： | 2017-07-14 |
Progress in research of family-based cohort study on common chronic non-communicable diseases in rural population in northern China |
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| Wang Mengying,Tang Xun,Qin Xueying,Wu Yiqun,Li Jin,Gao Pei,Huang Shaoping,Li N,Yang Dongli,Ren Tao,Wu Tao,Chen Dafang and Hu Yonghua. Progress in research of family-based cohort study on common chronic non-communicable diseases in rural population in northern China[J]. Chinese Journal of Epidemiology, 2018, 39(1): 94-97 |
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| Authors: | Wang Mengying Tang Xun Qin Xueying Wu Yiqun Li Jin Gao Pei Huang Shaoping Li N Yang Dongli Ren Tao Wu Tao Chen Dafang Hu Yonghua |
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| Affiliation: | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China,Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China,Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China,Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China,Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China,Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China,General Office, Fangshan District Center for Disease Control and Prevention, Beijing 102401, China,General Office, Fangshan District Center for Disease Control and Prevention, Beijing 102401, China,General Office, Fangshan District Health Bureau, Beijing 102401, China,Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China,Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China,Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China and Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China |
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| Abstract: | Family-based cohort study is a special type of study design, in which biological samples and environmental exposure information of the member in a family are collected and related follow up is conducted. Family-based cohort study can be applied to explore the effect of genetic factors, environmental factors, gene-gene interaction, and gene-environment interaction in the etiology of complex diseases. This paper summarizes the objectives, methods and results, as well as the opportunities and challenges of the family-based cohort study on common chronic non-communicable diseases in rural population in northern China. |
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| Keywords: | Hypertension Stroke Diabetes mellitus Family-based cohort study |
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