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德宏傣族景颇族自治州抗病毒治疗的HIV/AIDS糖尿病患病率及其相关因素分析
引用本文:叶润华,李静,姚仕堂,王继宝,曹东冬,章银娣,时允,李品银,许元武,魏华,肖桂芳,孙进廷,段星,王译葵,杨锦,何纳,丁盈盈,段松. 德宏傣族景颇族自治州抗病毒治疗的HIV/AIDS糖尿病患病率及其相关因素分析[J]. 中华流行病学杂志, 2019, 40(6): 654-659
作者姓名:叶润华  李静  姚仕堂  王继宝  曹东冬  章银娣  时允  李品银  许元武  魏华  肖桂芳  孙进廷  段星  王译葵  杨锦  何纳  丁盈盈  段松
作者单位:德宏傣族景颇族自治州疾病预防控制中心, 芒市 678400,复旦大学公共卫生学院流行病学教研室 公共卫生安全教育部重点实验室, 上海 200032,德宏傣族景颇族自治州疾病预防控制中心, 芒市 678400,德宏傣族景颇族自治州疾病预防控制中心, 芒市 678400,德宏傣族景颇族自治州人民医院, 芒市 678400,德宏傣族景颇族自治州人民医院, 芒市 678400,芒市人民医院 678400,瑞丽市民族医院 678600,陇川县人民医院 678700,盈江县人民医院 679300,德宏傣族景颇族自治州中医院, 芒市 678400,梁河县人民医院 679200,德宏傣族景颇族自治州疾病预防控制中心, 芒市 678400,德宏傣族景颇族自治州疾病预防控制中心, 芒市 678400,德宏傣族景颇族自治州疾病预防控制中心, 芒市 678400,复旦大学公共卫生学院流行病学教研室 公共卫生安全教育部重点实验室, 上海 200032,复旦大学公共卫生学院流行病学教研室 公共卫生安全教育部重点实验室, 上海 200032,德宏傣族景颇族自治州疾病预防控制中心, 芒市 678400
基金项目:国家科技重大专项(2018ZX10715006,2018ZX17021102-004);国家重点地区艾滋病防治项目
摘    要:目的 了解云南省德宏傣族景颇族自治州(德宏州)抗病毒治疗的HIV/AIDS糖尿病患病情况及其相关因素。方法 利用我国艾滋病防治基本信息系统下载德宏州HIV/AIDS抗病毒治疗数据库,并于2017年7月至2018年6月对德宏州≥18岁正在抗病毒治疗的HIV/AIDS开展横断面调查,并采集其静脉血检测其糖化血红蛋白(HbA1c)。糖尿病判定标准为符合其中任意一项者(HbA1c≥6.5%、基线FPG≥7.0 mmol/L、最近1次FPG≥7.0 mmol/L)。采用logistic回归分析抗病毒治疗的HIV/AIDS患有糖尿病的相关因素。结果 共纳入4 376例HIV/AIDS,年龄(43.7±10.1)岁,男性占53.8%(2 356/4 376),HCV阳性率为24.1%(1 055/4 376),HIV确诊阳性时间(8.9±3.8)年,治疗时间(6.8±2.9)年。糖尿病患病率为11.4%(500/4 376)。多因素logistic回归分析结果显示,抗病毒治疗的HIV/AIDS患糖尿病的相关危险因素包括≥40岁、男性、HCV阳性、基线BMI≥24.0 kg/m2、最近1次TG≥1.70 mmol/L、初始抗病毒治疗药物为依非韦伦(EFV)。结论 德宏州抗病毒治疗的HIV/AIDS糖尿病患病率为11.4%。对于抗病毒治疗的HIV/AIDS,应加强中老年、男性、HCV阳性、超重和高TG等糖尿病相关危险因素的预防与控制工作,需进一步研究EFV与糖尿病患病风险的可能关联。

关 键 词:艾滋病病毒  糖尿病  患病率  影响因素
收稿时间:2018-12-21

Prevalence and related factors on diabetes among HIV/AIDS receiving antiretroviral therapy in Dehong Dai and Jingpo Autonomous Prefecture
Ye Runhu,Li Jing,Yao Shitang,Wang Jibao,Cao Dongdong,Zhang Yindi,Shi Yun,Li Pinyin,Xu Yuanwu,Wei Hu,Xiao Guifang,Sun Jinting,Duan Xing,Wang Yikui,Yang Jin,He N,Ding Yingying and Duan Song. Prevalence and related factors on diabetes among HIV/AIDS receiving antiretroviral therapy in Dehong Dai and Jingpo Autonomous Prefecture[J]. Chinese Journal of Epidemiology, 2019, 40(6): 654-659
Authors:Ye Runhu  Li Jing  Yao Shitang  Wang Jibao  Cao Dongdong  Zhang Yindi  Shi Yun  Li Pinyin  Xu Yuanwu  Wei Hu  Xiao Guifang  Sun Jinting  Duan Xing  Wang Yikui  Yang Jin  He N  Ding Yingying  Duan Song
Affiliation:Dehong Dai and Jingpo Autonomous Prefecture Center for Disease Control and Prevention, Mangshi 678400, China,Department of Epidemiology, Key Laboratory of Public Health Safety of Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China,Dehong Dai and Jingpo Autonomous Prefecture Center for Disease Control and Prevention, Mangshi 678400, China,Dehong Dai and Jingpo Autonomous Prefecture Center for Disease Control and Prevention, Mangshi 678400, China,Dehong Dai and Jingpo Autonomous Prefecture People''s Hospital, Mangshi 678400, China,Dehong Dai and Jingpo Autonomous Prefecture People''s Hospital, Mangshi 678400, China,Mangshi City People''s Hospital, Mangshi 678400, China,Ruili City People''s Hospital, Ruili 678600, China,Longchuan County People''s Hospital, Longchuan 678700, China,Yingjiang County People''s Hospital, Yingjiang 679300, China,Dehong Dai and Jingpo Autonomous Prefecture Hospital of Traditional Chinese Medicine, Mangshi 678400, China,Lianghe County People''s Hospital, Lianghe 679200, China,Dehong Dai and Jingpo Autonomous Prefecture Center for Disease Control and Prevention, Mangshi 678400, China,Dehong Dai and Jingpo Autonomous Prefecture Center for Disease Control and Prevention, Mangshi 678400, China,Dehong Dai and Jingpo Autonomous Prefecture Center for Disease Control and Prevention, Mangshi 678400, China,Department of Epidemiology, Key Laboratory of Public Health Safety of Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China,Department of Epidemiology, Key Laboratory of Public Health Safety of Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China and Dehong Dai and Jingpo Autonomous Prefecture Center for Disease Control and Prevention, Mangshi 678400, China
Abstract:
Keywords:HIV  Diabetes  Prevalence  Related factors
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