A Retrospective Study of Culture-confirmed Mycobacterial Infection among Hospitalized HIV-infected Patients in Beijing,China |
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| Authors: | ZHAO Xiu Ying ZENG Zhao Ying HUA Wen Hao YU Yan Hua GUO Cai Ping ZHAO Xiu Qin DONG Hai Yan LIU Jie WAN Kang Lin |
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| Affiliation: | 1. Beijing Tsinghua Changgung Hospital, School of Clinic Medicine, Tsinghua University, Beijing 102218, China;2. Department of Clinical Laboratory, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China;3. Beijing Di''tan Hospital, Capital Medical University, Beijing 102206, China;4. Beijing You''an Hospital, Capital Medical University, Beijing 100069, China;5. National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, State Key Laboratory for Infectious Disease Prevention and Control, Beijing 102206, China |
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| Abstract: | A retrospective analysis was performed in two major HIV/AIDS referral hospitals in Beijing to evaluate the prevalence of Mycobacterium tuberculosis(MTB) and non-tuberculous mycobacterial(NTM) infections in HIV-infected patients. A total of 627 patients' data were reviewed, and 102(16.3%) patients were diagnosed with culture-confirmed mycobacterial infection, including 84 with MTB, 16 with NTM, and 2 with both MTB and NTM. The most frequent clinical complication by mycobacterial infection was pulmonary infection(48/102, 47.1%). The overall rates of multidrug-resistant TB(MDR-TB) and extensively drug-resistant TB(XDR-TB) were 11.9% and 3.4%, respectively. This study underlines the urgent need to intensify screening for mycobacteria coinfection with HIV and to prevent the spread of drug-resistant TB among HIV-infected patients. |
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| Keywords: | Correspondence should be addressed to ZHAO Xiu Ying Tel: 86-10-56119198 |
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